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› Forums › General Melanoma Community › Gcmaf

  • Post
    • December 21, 2012 at 3:55 pm
    bball
    Participant

      Has anyone tried Gcmaf to increase immune system

      Has anyone tried Gcmaf to increase immune system

    Viewing 20 reply threads
    • Replies
        • December 21, 2012 at 4:00 pm
        Janner
        Participant

          If you do a search on this site for GM-CSF or Leukine, you will find others who have used it in trials or stand-alone.  Note the spelling which is different from your subject.

          (Granulocyte macrophage colony-stimulating factor)

          • December 21, 2012 at 4:00 pm
          Janner
          Participant

            If you do a search on this site for GM-CSF or Leukine, you will find others who have used it in trials or stand-alone.  Note the spelling which is different from your subject.

            (Granulocyte macrophage colony-stimulating factor)

              • December 21, 2012 at 5:12 pm
              _Paul_
              Participant
                There is a phase 1 clinical trial underway at Johns Hopkins (J1112) where they are determining the safety of administering a GVAX vaccine. This consists of lab-grown melanoma cells irradiated to prevent reproduction and genetically altered to secrete GMCSF. You can google “melanoma gvax” for more info.

                – Paul

                • December 21, 2012 at 5:12 pm
                _Paul_
                Participant
                  There is a phase 1 clinical trial underway at Johns Hopkins (J1112) where they are determining the safety of administering a GVAX vaccine. This consists of lab-grown melanoma cells irradiated to prevent reproduction and genetically altered to secrete GMCSF. You can google “melanoma gvax” for more info.

                  – Paul

                  • December 21, 2012 at 5:12 pm
                  _Paul_
                  Participant
                    There is a phase 1 clinical trial underway at Johns Hopkins (J1112) where they are determining the safety of administering a GVAX vaccine. This consists of lab-grown melanoma cells irradiated to prevent reproduction and genetically altered to secrete GMCSF. You can google “melanoma gvax” for more info.

                    – Paul

                  • December 21, 2012 at 4:00 pm
                  Janner
                  Participant

                    If you do a search on this site for GM-CSF or Leukine, you will find others who have used it in trials or stand-alone.  Note the spelling which is different from your subject.

                    (Granulocyte macrophage colony-stimulating factor)

                    • December 21, 2012 at 5:40 pm
                    killmel
                    Participant

                      I took Gm-csf and at nine months I had a recurrence. (14 days on, 14 days off)

                      This drug increases your Tcells but your Tcells need to know to kill the cancer 

                      • December 21, 2012 at 5:40 pm
                      killmel
                      Participant

                        I took Gm-csf and at nine months I had a recurrence. (14 days on, 14 days off)

                        This drug increases your Tcells but your Tcells need to know to kill the cancer 

                        • December 21, 2012 at 5:40 pm
                        killmel
                        Participant

                          I took Gm-csf and at nine months I had a recurrence. (14 days on, 14 days off)

                          This drug increases your Tcells but your Tcells need to know to kill the cancer 

                          • December 21, 2012 at 11:49 pm
                          Ann from Iowa
                          Participant

                            My husband did one year of Leukine and is now 4 1/2 years out from his original nodular melanoma diagnosis.  You can read his profile to learn the details of his melanoma and treatment.  It has been two years now since he stopped treatment which also included radiation to his left axillary and the removal of 32 lymph nodes to that area.  He is just fine, NED at this point.  As I said, please read his profile, it is under Ann from Iowa.    Or you can write me directly at [email protected] if you want more information.  Dennis is Stage IIIB, we have a friend who is Stage IV and was treated at the Mayo Clinic with a combo drug which included Leukine.  She is now 10 years from original diagnosis.  Another lady we know is also Stage IV and has been on Leukine for 5 years.  Her doctor at Mayo Clinic said that as long as she stays NED on it they will continue the treatment.  I realize that most doctors no longer use Leukine for treatment as his Dr. said that he would not considering the stage of cancer he had when they used it.  He did not do Leukine at Stage IIB, nothing but watch and wait at that time.  Leukine begain after he had a recurrance in his lymph nodes, 5 cm with extranodal extension.  For him is either has worked or at least is giving him quite an extended time to recurrance.  Very few side effects either.   Good luck.

                            • December 21, 2012 at 11:49 pm
                            Ann from Iowa
                            Participant

                              My husband did one year of Leukine and is now 4 1/2 years out from his original nodular melanoma diagnosis.  You can read his profile to learn the details of his melanoma and treatment.  It has been two years now since he stopped treatment which also included radiation to his left axillary and the removal of 32 lymph nodes to that area.  He is just fine, NED at this point.  As I said, please read his profile, it is under Ann from Iowa.    Or you can write me directly at [email protected] if you want more information.  Dennis is Stage IIIB, we have a friend who is Stage IV and was treated at the Mayo Clinic with a combo drug which included Leukine.  She is now 10 years from original diagnosis.  Another lady we know is also Stage IV and has been on Leukine for 5 years.  Her doctor at Mayo Clinic said that as long as she stays NED on it they will continue the treatment.  I realize that most doctors no longer use Leukine for treatment as his Dr. said that he would not considering the stage of cancer he had when they used it.  He did not do Leukine at Stage IIB, nothing but watch and wait at that time.  Leukine begain after he had a recurrance in his lymph nodes, 5 cm with extranodal extension.  For him is either has worked or at least is giving him quite an extended time to recurrance.  Very few side effects either.   Good luck.

                              • December 21, 2012 at 11:49 pm
                              Ann from Iowa
                              Participant

                                My husband did one year of Leukine and is now 4 1/2 years out from his original nodular melanoma diagnosis.  You can read his profile to learn the details of his melanoma and treatment.  It has been two years now since he stopped treatment which also included radiation to his left axillary and the removal of 32 lymph nodes to that area.  He is just fine, NED at this point.  As I said, please read his profile, it is under Ann from Iowa.    Or you can write me directly at [email protected] if you want more information.  Dennis is Stage IIIB, we have a friend who is Stage IV and was treated at the Mayo Clinic with a combo drug which included Leukine.  She is now 10 years from original diagnosis.  Another lady we know is also Stage IV and has been on Leukine for 5 years.  Her doctor at Mayo Clinic said that as long as she stays NED on it they will continue the treatment.  I realize that most doctors no longer use Leukine for treatment as his Dr. said that he would not considering the stage of cancer he had when they used it.  He did not do Leukine at Stage IIB, nothing but watch and wait at that time.  Leukine begain after he had a recurrance in his lymph nodes, 5 cm with extranodal extension.  For him is either has worked or at least is giving him quite an extended time to recurrance.  Very few side effects either.   Good luck.

                                • December 22, 2012 at 5:28 am
                                Tracy Seattle
                                Participant
                                  I have researched it some but don’t know anyone who has tried it for Melanoma. I know someone who has seen positive results in treating Lyme disease. I don’t think any mainstream cancer doctors are using it. I think it may be considered more of an alternative therapy. If you decide to try it, I would be very interested in your results.
                                  • December 22, 2012 at 5:28 am
                                  Tracy Seattle
                                  Participant
                                    I have researched it some but don’t know anyone who has tried it for Melanoma. I know someone who has seen positive results in treating Lyme disease. I don’t think any mainstream cancer doctors are using it. I think it may be considered more of an alternative therapy. If you decide to try it, I would be very interested in your results.
                                    • December 22, 2012 at 5:28 am
                                    Tracy Seattle
                                    Participant
                                      I have researched it some but don’t know anyone who has tried it for Melanoma. I know someone who has seen positive results in treating Lyme disease. I don’t think any mainstream cancer doctors are using it. I think it may be considered more of an alternative therapy. If you decide to try it, I would be very interested in your results.
                                      • December 26, 2012 at 2:26 am
                                      Roxy1453
                                      Participant
                                        I’m stage IV and took GM-CSF for a year. It kept things at bay but as soon as I went off things started up again. I guess if you stay on it, it helps but it’s not fun. You give yourself a shot everyday for two weeks then you’re off for two. It has to be refrigerated and if you have to travel it’s a pain.

                                        Good luck,

                                        Nancy

                                        • December 26, 2012 at 2:26 am
                                        Roxy1453
                                        Participant
                                          I’m stage IV and took GM-CSF for a year. It kept things at bay but as soon as I went off things started up again. I guess if you stay on it, it helps but it’s not fun. You give yourself a shot everyday for two weeks then you’re off for two. It has to be refrigerated and if you have to travel it’s a pain.

                                          Good luck,

                                          Nancy

                                          • December 26, 2012 at 2:26 am
                                          Roxy1453
                                          Participant
                                            I’m stage IV and took GM-CSF for a year. It kept things at bay but as soon as I went off things started up again. I guess if you stay on it, it helps but it’s not fun. You give yourself a shot everyday for two weeks then you’re off for two. It has to be refrigerated and if you have to travel it’s a pain.

                                            Good luck,

                                            Nancy

                                            • December 26, 2012 at 4:26 am
                                            LynnLuc
                                            Participant

                                              My onc suggested it after I had surgery. I am stage 4 and had a 6.8 cent melanoma removed from my lymph nodes. The thing is my oc also told me there has been no evidence that the Leukine injections would prolong reoccurance AND a studies from the Jonsson Center (UCLA) showed it had no benefit whatsoever if the melanoma was in the lymph nodes…I opted not to do it. I am in a anti pd 1 /vaccine trial and been NED for over 2 yrs 9 months.

                                              • December 26, 2012 at 4:26 am
                                              LynnLuc
                                              Participant

                                                My onc suggested it after I had surgery. I am stage 4 and had a 6.8 cent melanoma removed from my lymph nodes. The thing is my oc also told me there has been no evidence that the Leukine injections would prolong reoccurance AND a studies from the Jonsson Center (UCLA) showed it had no benefit whatsoever if the melanoma was in the lymph nodes…I opted not to do it. I am in a anti pd 1 /vaccine trial and been NED for over 2 yrs 9 months.

                                                • December 26, 2012 at 4:26 am
                                                LynnLuc
                                                Participant

                                                  My onc suggested it after I had surgery. I am stage 4 and had a 6.8 cent melanoma removed from my lymph nodes. The thing is my oc also told me there has been no evidence that the Leukine injections would prolong reoccurance AND a studies from the Jonsson Center (UCLA) showed it had no benefit whatsoever if the melanoma was in the lymph nodes…I opted not to do it. I am in a anti pd 1 /vaccine trial and been NED for over 2 yrs 9 months.

                                                  • December 19, 2014 at 10:55 am
                                                  rick1981
                                                  Participant

                                                    Does anyone know if there have been any new studies in GCMAF since 2012? Or more personal experiences? Thanks, Rick

                                                    • December 19, 2014 at 10:55 am
                                                    rick1981
                                                    Participant

                                                      Does anyone know if there have been any new studies in GCMAF since 2012? Or more personal experiences? Thanks, Rick

                                                      • December 19, 2014 at 10:55 am
                                                      rick1981
                                                      Participant

                                                        Does anyone know if there have been any new studies in GCMAF since 2012? Or more personal experiences? Thanks, Rick

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