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FNA question

Forums General Melanoma Community FNA question

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    swissie
    Participant

    Hello everyone,

    I haven't posted in a long time.
    Short history, Stage IIIb since July 2009, started double blind trial with 10 mg ipi / placebo in September 2010.
    Ended this trial on own request after 8th infusion due to side effects (fatigue and increase of spleen).

    All my scans have been clean so far.
    Half a year ago, I had a swollen lymph node in my right groin (the original melanoma was on my left knee, the met in my left groin).
    Had an FNA which came out as a reactive lymph node.

    Hello everyone,

    I haven't posted in a long time.
    Short history, Stage IIIb since July 2009, started double blind trial with 10 mg ipi / placebo in September 2010.
    Ended this trial on own request after 8th infusion due to side effects (fatigue and increase of spleen).

    All my scans have been clean so far.
    Half a year ago, I had a swollen lymph node in my right groin (the original melanoma was on my left knee, the met in my left groin).
    Had an FNA which came out as a reactive lymph node.

    Last week I had a second biopsy (increase from 2.2 to 3.5 cm), which is declared a reactive lymph node again.
    Off course this is great news.

    However, there is nothing mentioned about any melanoma marker testing.

    Can one say a lymph node is reactive, just based on the kappa-lambda ration of 1.1 :1 and the existance of 66% CD3 positiveT-cells, 27%  CD19 positive B-cells  and the lack of CD5, CD10 and CD23?

    It would be great if anyone can explain this (response from my doctor: "I guess if the cell line is clear (all lymphocytic cells) there is no need for melanoma markers").

     

    Thanks for your help,
    Swissie

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