› Forums › General Melanoma Community › FDA Approves Ipilimumab for Stage III Melanoma Patients
- This topic has 12 replies, 3 voices, and was last updated 8 years, 6 months ago by jenny22.
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- October 28, 2015 at 11:44 pm
All,
Great news! This evening the FDA approved ipilimumab (Yervoy) as an adjuvant therapy for Stage III melanoma patients who have had their tumors removed through surgery.This is the first new adjuvant treatment in 20 years! The MRF issued a statement with more information, which you can read by following this link: http://www.melanoma.org/about-us/news-press-room/press-releases/fda-approves-first-new-adjuvant-treatment-stage-iii-melanoma
Lauren – MRF
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- October 28, 2015 at 11:51 pm
Wow, I was not expecting that. I wonder if BMS will cancel my Clinical trial for IPI/NIVO now as there really is no need? Quite honestly it would be cheaper to me to quit my trial and just get the Yervoy as my yearly out of pocket has been met.
Tom
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- October 28, 2015 at 11:51 pm
Wow, I was not expecting that. I wonder if BMS will cancel my Clinical trial for IPI/NIVO now as there really is no need? Quite honestly it would be cheaper to me to quit my trial and just get the Yervoy as my yearly out of pocket has been met.
Tom
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- October 28, 2015 at 11:51 pm
Wow, I was not expecting that. I wonder if BMS will cancel my Clinical trial for IPI/NIVO now as there really is no need? Quite honestly it would be cheaper to me to quit my trial and just get the Yervoy as my yearly out of pocket has been met.
Tom
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- October 29, 2015 at 12:22 am
It is great news, but i can't help but wonder now…..
Had instranist recurrrence last NOV, complete resection…..never was able to have SNB …..DOCS all "assuming" negative node status…..now making me stage IIIB….had vaccine trial at NYU Feb- May……
Now wonder if IPI would have been better……Being treated at NYU, with ANNA Pavlick…love her….
Just wondering if something to ask about.
Thoughts anyone????
TKs,
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- October 29, 2015 at 12:22 am
It is great news, but i can't help but wonder now…..
Had instranist recurrrence last NOV, complete resection…..never was able to have SNB …..DOCS all "assuming" negative node status…..now making me stage IIIB….had vaccine trial at NYU Feb- May……
Now wonder if IPI would have been better……Being treated at NYU, with ANNA Pavlick…love her….
Just wondering if something to ask about.
Thoughts anyone????
TKs,
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- October 29, 2015 at 12:22 am
It is great news, but i can't help but wonder now…..
Had instranist recurrrence last NOV, complete resection…..never was able to have SNB …..DOCS all "assuming" negative node status…..now making me stage IIIB….had vaccine trial at NYU Feb- May……
Now wonder if IPI would have been better……Being treated at NYU, with ANNA Pavlick…love her….
Just wondering if something to ask about.
Thoughts anyone????
TKs,
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- October 29, 2015 at 12:55 am
Here is something to think about that my oncologist Dr Jason Luke had about ipi as adjuvant. Ipi has shown a 25% success rate as an adjuvant and a 22% success rate in stage 4. He sees no statistical advantage to taking it as adjuvant because the side effects can be severe. His opinion is why put yourself through the chance of immune related events when there is a chance the cancer may not return. If it does you statistically have the same chance of responding. I hope the pd-1 drugs show a much better efficacy as adjuvant therapy which remains to be seen.-
- November 4, 2015 at 8:02 pm
Hi Janieth29-
Intereresting point made by your oncologist……I am hearing similar things…..just met with Dr. Coit, surgical oncologist at MSKCC…..i asked him his opintion and he said he thinks IPI will be a "tough sell" in the adjuvant setting due to the extremely high toxity profile……he is hopeful that PD1 treatments will soon be an option without the IPI side effects……my MEd. ONC also seems hesitant on IPI for me in this setting….
In spite of all this, I feel the need to do SOMETHING to ZAP any cells that may be flaoting aorund somewhere…..after 2 recurrences it is scary to wonder where they are going next….Radiation is a good alternative for local "Stuff', but the goal is to keep it from going anywhere else!
Lets hope we soon have some other options for adjuvant treatments.
Best,
jenny
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- November 4, 2015 at 8:02 pm
Hi Janieth29-
Intereresting point made by your oncologist……I am hearing similar things…..just met with Dr. Coit, surgical oncologist at MSKCC…..i asked him his opintion and he said he thinks IPI will be a "tough sell" in the adjuvant setting due to the extremely high toxity profile……he is hopeful that PD1 treatments will soon be an option without the IPI side effects……my MEd. ONC also seems hesitant on IPI for me in this setting….
In spite of all this, I feel the need to do SOMETHING to ZAP any cells that may be flaoting aorund somewhere…..after 2 recurrences it is scary to wonder where they are going next….Radiation is a good alternative for local "Stuff', but the goal is to keep it from going anywhere else!
Lets hope we soon have some other options for adjuvant treatments.
Best,
jenny
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- November 4, 2015 at 8:02 pm
Hi Janieth29-
Intereresting point made by your oncologist……I am hearing similar things…..just met with Dr. Coit, surgical oncologist at MSKCC…..i asked him his opintion and he said he thinks IPI will be a "tough sell" in the adjuvant setting due to the extremely high toxity profile……he is hopeful that PD1 treatments will soon be an option without the IPI side effects……my MEd. ONC also seems hesitant on IPI for me in this setting….
In spite of all this, I feel the need to do SOMETHING to ZAP any cells that may be flaoting aorund somewhere…..after 2 recurrences it is scary to wonder where they are going next….Radiation is a good alternative for local "Stuff', but the goal is to keep it from going anywhere else!
Lets hope we soon have some other options for adjuvant treatments.
Best,
jenny
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- October 29, 2015 at 12:55 am
Here is something to think about that my oncologist Dr Jason Luke had about ipi as adjuvant. Ipi has shown a 25% success rate as an adjuvant and a 22% success rate in stage 4. He sees no statistical advantage to taking it as adjuvant because the side effects can be severe. His opinion is why put yourself through the chance of immune related events when there is a chance the cancer may not return. If it does you statistically have the same chance of responding. I hope the pd-1 drugs show a much better efficacy as adjuvant therapy which remains to be seen. -
- October 29, 2015 at 12:55 am
Here is something to think about that my oncologist Dr Jason Luke had about ipi as adjuvant. Ipi has shown a 25% success rate as an adjuvant and a 22% success rate in stage 4. He sees no statistical advantage to taking it as adjuvant because the side effects can be severe. His opinion is why put yourself through the chance of immune related events when there is a chance the cancer may not return. If it does you statistically have the same chance of responding. I hope the pd-1 drugs show a much better efficacy as adjuvant therapy which remains to be seen.
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