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FDA Approves First Combination Therapy for Advanced Melanoma
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FDA Approves First Combination Therapy for Advanced Melanoma

› Forums › General Melanoma Community › FDA Approves First Combination Therapy for Advanced Melanoma

  • Post
    • January 9, 2014 at 3:47 pm
    lsmith – MRF
    Keymaster

      Good morning,

      The FDA just approved the first-ever combination therapy for advanced melanoma! The combination involves a MEK inhibitor, trametinib, and a BRAF inhibitor, dabrafenib. Both drugs (developed by GSK) were approved by the FDA in May 2013 for use as single therapies. The MRF issued a statement on the approval, which you can read here.

      Lauren – MRF

       

    Viewing 8 reply threads
    • Replies
        • January 9, 2014 at 11:57 pm
        aldakota22
        Participant

          All good news.Just another weapon against the beast.Everyone out there fight as hard as you can for the day is soon we will victor over melanoma.It is all possible through the new targeted drugs approach.   aldakota22

           

           

          • January 9, 2014 at 11:57 pm
          aldakota22
          Participant

            All good news.Just another weapon against the beast.Everyone out there fight as hard as you can for the day is soon we will victor over melanoma.It is all possible through the new targeted drugs approach.   aldakota22

             

             

            • January 9, 2014 at 11:57 pm
            aldakota22
            Participant

              All good news.Just another weapon against the beast.Everyone out there fight as hard as you can for the day is soon we will victor over melanoma.It is all possible through the new targeted drugs approach.   aldakota22

               

               

              • January 12, 2014 at 4:52 pm
              Michelem
              Participant

                So this would be only for people who have the BRAF mutation? 

                  • January 12, 2014 at 5:24 pm
                  POW
                  Participant

                    Yes. BRAF mutated only.

                    • January 12, 2014 at 5:24 pm
                    POW
                    Participant

                      Yes. BRAF mutated only.

                      • January 12, 2014 at 5:24 pm
                      POW
                      Participant

                        Yes. BRAF mutated only.

                        • January 13, 2014 at 3:01 pm
                        JerryfromFauq
                        Participant

                          This Combo is only for BRAF + patients.  Mek inhibitors are also being tested in conjunction with other drugs to see their effect, eg Gleevec and MEK, and other combinations.  Hurrry and get those studies done!

                          • January 13, 2014 at 3:01 pm
                          JerryfromFauq
                          Participant

                            This Combo is only for BRAF + patients.  Mek inhibitors are also being tested in conjunction with other drugs to see their effect, eg Gleevec and MEK, and other combinations.  Hurrry and get those studies done!

                            • January 13, 2014 at 3:01 pm
                            JerryfromFauq
                            Participant

                              This Combo is only for BRAF + patients.  Mek inhibitors are also being tested in conjunction with other drugs to see their effect, eg Gleevec and MEK, and other combinations.  Hurrry and get those studies done!

                            • January 12, 2014 at 4:52 pm
                            Michelem
                            Participant

                              So this would be only for people who have the BRAF mutation? 

                              • January 12, 2014 at 4:52 pm
                              Michelem
                              Participant

                                So this would be only for people who have the BRAF mutation? 

                                • January 12, 2014 at 9:52 pm
                                casagrayson
                                Participant

                                  A good friend of mine has been on this combination since October.  Recent PET scans show no new tumors, and all of his other tumors except one have shrunk significantly.  He's having surgery this week to remove that stubborn one.  He looks great and feels good!  (Such a great thing to see after watching him go through biochemo!) 

                                  • January 12, 2014 at 9:52 pm
                                  casagrayson
                                  Participant

                                    A good friend of mine has been on this combination since October.  Recent PET scans show no new tumors, and all of his other tumors except one have shrunk significantly.  He's having surgery this week to remove that stubborn one.  He looks great and feels good!  (Such a great thing to see after watching him go through biochemo!) 

                                    • January 12, 2014 at 9:52 pm
                                    casagrayson
                                    Participant

                                      A good friend of mine has been on this combination since October.  Recent PET scans show no new tumors, and all of his other tumors except one have shrunk significantly.  He's having surgery this week to remove that stubborn one.  He looks great and feels good!  (Such a great thing to see after watching him go through biochemo!) 

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