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E7080 phase 2 pluse Dacarbazine
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E7080 phase 2 pluse Dacarbazine

› Forums › General Melanoma Community › E7080 phase 2 pluse Dacarbazine

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    • April 27, 2012 at 4:59 pm
    Woodlands
    Participant

      Hi,

      We live in Wales, United Kingdom, my husband is Stage IV and 8 weeks ago finished 8 rounds of dacarbazine with the trial drug E7080, he is currently on a maintanance programme with the E7080.

      In the UK we only normally give 6 rounds of Dacarbazine but as this is an American and Japanese trial he has had 8 rounds, he tollerated everything really well for the past week has had debilitating fatigue and pins and needles in his feet.  he is being monitored closely and is having a weeks break from the E7080. 

      Hi,

      We live in Wales, United Kingdom, my husband is Stage IV and 8 weeks ago finished 8 rounds of dacarbazine with the trial drug E7080, he is currently on a maintanance programme with the E7080.

      In the UK we only normally give 6 rounds of Dacarbazine but as this is an American and Japanese trial he has had 8 rounds, he tollerated everything really well for the past week has had debilitating fatigue and pins and needles in his feet.  he is being monitored closely and is having a weeks break from the E7080. 

      He has had really good results and is now stable but this fatigue and the pins and needles is really getting him down.

      I wondered as we in the Uk are not aware of the side effects of 8 doses of dacarbazine has anyone out there had any similar symptoms, if so any help or advise would be appreciated!

      Many thanks x

       

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