› Forums › General Melanoma Community › Do normal moles (Non Atypical Moles) Have any risk?
- This topic has 9 replies, 2 voices, and was last updated 7 years, 10 months ago by Janner.
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- June 24, 2016 at 1:02 am
Could a normal mole turn into melanoma? Extremely unlikely. There are times where people who have had some major trauma and then had something change to melanoma. But benign and mildly atypical moles really carry little risk. Severely atypical moles carry the highest risk but no certainty that they will ever change.
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- June 24, 2016 at 12:10 pm
Janner, on this subject how do dernatologists tell an atypical mole? I have several funny looking ones that don't have asymmetry, clear borders, and are various shades of the same brownish color. These looked atypical but when they were biopsied they were normal moles with no atypia.
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- June 24, 2016 at 2:40 pm
They look at basically two things. First is the cell structure itself. They stain the melanocytes and look at the cell to see if it displays any abnormal features. Then they look at the architecture of the skin sample. Are the melanocytes distributed normally? Growing along dermal/epidermal junction? Are there many immature cells or an abnormal number of cells? Things along those lines. So looking at the outward appearance doesn't really say anything about the cell structure and how the cells are distributed beneath the visible layer. You can have normal looking cells but some atypical architecture and visa versa. So the final determination on how atypical something may or may not be is a combination of cell atypia and architectural atypia.
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- June 24, 2016 at 2:40 pm
They look at basically two things. First is the cell structure itself. They stain the melanocytes and look at the cell to see if it displays any abnormal features. Then they look at the architecture of the skin sample. Are the melanocytes distributed normally? Growing along dermal/epidermal junction? Are there many immature cells or an abnormal number of cells? Things along those lines. So looking at the outward appearance doesn't really say anything about the cell structure and how the cells are distributed beneath the visible layer. You can have normal looking cells but some atypical architecture and visa versa. So the final determination on how atypical something may or may not be is a combination of cell atypia and architectural atypia.
-
- June 24, 2016 at 2:40 pm
They look at basically two things. First is the cell structure itself. They stain the melanocytes and look at the cell to see if it displays any abnormal features. Then they look at the architecture of the skin sample. Are the melanocytes distributed normally? Growing along dermal/epidermal junction? Are there many immature cells or an abnormal number of cells? Things along those lines. So looking at the outward appearance doesn't really say anything about the cell structure and how the cells are distributed beneath the visible layer. You can have normal looking cells but some atypical architecture and visa versa. So the final determination on how atypical something may or may not be is a combination of cell atypia and architectural atypia.
-
- June 24, 2016 at 12:10 pm
Janner, on this subject how do dernatologists tell an atypical mole? I have several funny looking ones that don't have asymmetry, clear borders, and are various shades of the same brownish color. These looked atypical but when they were biopsied they were normal moles with no atypia.
-
- June 24, 2016 at 12:10 pm
Janner, on this subject how do dernatologists tell an atypical mole? I have several funny looking ones that don't have asymmetry, clear borders, and are various shades of the same brownish color. These looked atypical but when they were biopsied they were normal moles with no atypia.
-
- June 24, 2016 at 1:02 am
Could a normal mole turn into melanoma? Extremely unlikely. There are times where people who have had some major trauma and then had something change to melanoma. But benign and mildly atypical moles really carry little risk. Severely atypical moles carry the highest risk but no certainty that they will ever change.
-
- June 24, 2016 at 1:02 am
Could a normal mole turn into melanoma? Extremely unlikely. There are times where people who have had some major trauma and then had something change to melanoma. But benign and mildly atypical moles really carry little risk. Severely atypical moles carry the highest risk but no certainty that they will ever change.
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Tagged: cutaneous melanoma
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