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Do normal moles (Non Atypical Moles) Have any risk?

Forums General Melanoma Community Do normal moles (Non Atypical Moles) Have any risk?

  • Post
    UriahPH
    Participant
      I also hear that moderate or more cases highly Atypical moles carry a risk. What is the risk of Melanoma forming in a normal moles?
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        Janner
        Participant

          Could a normal mole turn into melanoma?  Extremely unlikely.  There are times where people who have had some major trauma and then had something change to melanoma.  But benign and mildly atypical moles really carry little risk.  Severely atypical moles carry the highest risk but no certainty that they will ever change. 

            Scared99
            Participant

              Janner, on this subject how do dernatologists tell an atypical mole? I have several funny looking ones that don't have asymmetry, clear borders, and are various shades of the same brownish color.   These looked atypical but when they were biopsied they were normal moles with no atypia. 

              Janner
              Participant

                They look at basically two things.  First is the cell structure itself.  They stain the melanocytes and look at the cell to see if it displays any abnormal features. Then they look at the architecture of the skin sample.  Are the melanocytes distributed normally?  Growing along dermal/epidermal junction?  Are there many immature cells or an abnormal number of cells?  Things along those lines.  So looking at the outward appearance doesn't really say anything about the cell structure and how the cells are distributed beneath the visible layer.  You can have normal looking cells but some atypical architecture and visa versa.  So the final determination on how atypical something may or may not be is a combination of cell atypia and architectural atypia.

                Janner
                Participant

                  They look at basically two things.  First is the cell structure itself.  They stain the melanocytes and look at the cell to see if it displays any abnormal features. Then they look at the architecture of the skin sample.  Are the melanocytes distributed normally?  Growing along dermal/epidermal junction?  Are there many immature cells or an abnormal number of cells?  Things along those lines.  So looking at the outward appearance doesn't really say anything about the cell structure and how the cells are distributed beneath the visible layer.  You can have normal looking cells but some atypical architecture and visa versa.  So the final determination on how atypical something may or may not be is a combination of cell atypia and architectural atypia.

                  Janner
                  Participant

                    They look at basically two things.  First is the cell structure itself.  They stain the melanocytes and look at the cell to see if it displays any abnormal features. Then they look at the architecture of the skin sample.  Are the melanocytes distributed normally?  Growing along dermal/epidermal junction?  Are there many immature cells or an abnormal number of cells?  Things along those lines.  So looking at the outward appearance doesn't really say anything about the cell structure and how the cells are distributed beneath the visible layer.  You can have normal looking cells but some atypical architecture and visa versa.  So the final determination on how atypical something may or may not be is a combination of cell atypia and architectural atypia.

                    Scared99
                    Participant

                      Janner, on this subject how do dernatologists tell an atypical mole? I have several funny looking ones that don't have asymmetry, clear borders, and are various shades of the same brownish color.   These looked atypical but when they were biopsied they were normal moles with no atypia. 

                      Scared99
                      Participant

                        Janner, on this subject how do dernatologists tell an atypical mole? I have several funny looking ones that don't have asymmetry, clear borders, and are various shades of the same brownish color.   These looked atypical but when they were biopsied they were normal moles with no atypia. 

                      Janner
                      Participant

                        Could a normal mole turn into melanoma?  Extremely unlikely.  There are times where people who have had some major trauma and then had something change to melanoma.  But benign and mildly atypical moles really carry little risk.  Severely atypical moles carry the highest risk but no certainty that they will ever change. 

                        Janner
                        Participant

                          Could a normal mole turn into melanoma?  Extremely unlikely.  There are times where people who have had some major trauma and then had something change to melanoma.  But benign and mildly atypical moles really carry little risk.  Severely atypical moles carry the highest risk but no certainty that they will ever change. 

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