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desparate need of help with path report

Forums Cutaneous Melanoma Community desparate need of help with path report

  • Post
    KnowThyself
    Participant
      So the lesion is on my upper ear helix…I’ve had a biopsy, excision, WLE, and now they want to take more because the margins are not clean… however, the path report seems to contradict itself, here’s the meat of it:
      “Severly atypical dermal and epidermal melanocytic priliferation present at tissue edges…the lesion is histologically difficult and borderline in nature. Although a benign lesion is favored, we are not able to exclude malignant melanoma. The differential diagnosis includes a .8mm deep, nonulcerated, malignant melanoma stage pt1a, with no mitotic activity.. re-excision along with margin of uninvolved skin recommended….
      So basically, id like to know if its benign, or malignant…and why they wouldn’t be able to tell the difference…I don’t want to have more done if its not needed, seems how this time a skin graft won’t be able to cut it, he said it’ll have to be larger, and get into plastic surgery….. I don’t know what to do, I don’t want to leave it alone if there are cancerous cells, if they ARE in fact cancerous…but no one seems to know! And with no insurance, and a low tolerance for pain, I need a better answer than ‘borderline’….

      Help!?!?!?!?

    Viewing 2 reply threads
    • Replies
        Janner
        Participant

          Severely atypical lesions might technically be benign, but they are as close to melanoma in situ as you can get and still be "benign".  Even then, it's usually recommended to have 5mm margins on severely atypical lesions — just like melanoma in situ (cancer).  It can be a fine line distinguishing between the two diagnosis — but the treatment is actually the same.  There is no black and white between melanoma in situ and severely atypical.  One doc might say cancer, the other benign.  Basically, they look at a bunch of factors present and decide how atypical each one is.  Then they come up with a consensus.  So, if you think of a scale from 1-10 and 10 is melanoma in situ, a severely atypical lesion could be anywhere from a 7-9.9.   One factor might say cancer while another one says "atypical".  Add them all up and what do you get?  Pathology is not an exact science and much depends on the experience of the pathologist.

          So, now back to your original question, should you have the extra margins taken if you have severely atypical cells at the margins?  If it were me, I'd say yes.  To date, the very BEST "cure" for melanoma is surgery at the original site.  Ears are higher risk areas and getting it all now seems to me to be the best way to go.  This is my opinion.  You have to make the final determination on what works best for YOU.  No insurance sucks, but it would be even harder later to pay for treatments ($$$$$$), etc., if this were to spread. 

          Best wishes,

          Janner

          Janner
          Participant

            Severely atypical lesions might technically be benign, but they are as close to melanoma in situ as you can get and still be "benign".  Even then, it's usually recommended to have 5mm margins on severely atypical lesions — just like melanoma in situ (cancer).  It can be a fine line distinguishing between the two diagnosis — but the treatment is actually the same.  There is no black and white between melanoma in situ and severely atypical.  One doc might say cancer, the other benign.  Basically, they look at a bunch of factors present and decide how atypical each one is.  Then they come up with a consensus.  So, if you think of a scale from 1-10 and 10 is melanoma in situ, a severely atypical lesion could be anywhere from a 7-9.9.   One factor might say cancer while another one says "atypical".  Add them all up and what do you get?  Pathology is not an exact science and much depends on the experience of the pathologist.

            So, now back to your original question, should you have the extra margins taken if you have severely atypical cells at the margins?  If it were me, I'd say yes.  To date, the very BEST "cure" for melanoma is surgery at the original site.  Ears are higher risk areas and getting it all now seems to me to be the best way to go.  This is my opinion.  You have to make the final determination on what works best for YOU.  No insurance sucks, but it would be even harder later to pay for treatments ($$$$$$), etc., if this were to spread. 

            Best wishes,

            Janner

            Janner
            Participant

              Severely atypical lesions might technically be benign, but they are as close to melanoma in situ as you can get and still be "benign".  Even then, it's usually recommended to have 5mm margins on severely atypical lesions — just like melanoma in situ (cancer).  It can be a fine line distinguishing between the two diagnosis — but the treatment is actually the same.  There is no black and white between melanoma in situ and severely atypical.  One doc might say cancer, the other benign.  Basically, they look at a bunch of factors present and decide how atypical each one is.  Then they come up with a consensus.  So, if you think of a scale from 1-10 and 10 is melanoma in situ, a severely atypical lesion could be anywhere from a 7-9.9.   One factor might say cancer while another one says "atypical".  Add them all up and what do you get?  Pathology is not an exact science and much depends on the experience of the pathologist.

              So, now back to your original question, should you have the extra margins taken if you have severely atypical cells at the margins?  If it were me, I'd say yes.  To date, the very BEST "cure" for melanoma is surgery at the original site.  Ears are higher risk areas and getting it all now seems to me to be the best way to go.  This is my opinion.  You have to make the final determination on what works best for YOU.  No insurance sucks, but it would be even harder later to pay for treatments ($$$$$$), etc., if this were to spread. 

              Best wishes,

              Janner

              becky15
              Participant

                Janner, your reply revolves around the opening poster having a severely atypical lesion versus melanoma in situ.  The differential diagnosis, however, was a stage 1a melanoma of 0.8mm in depth which is not melanoma in situ.

                 

                 

                becky15
                Participant

                  Janner, your reply revolves around the opening poster having a severely atypical lesion versus melanoma in situ.  The differential diagnosis, however, was a stage 1a melanoma of 0.8mm in depth which is not melanoma in situ.

                   

                   

                  becky15
                  Participant

                    Janner, your reply revolves around the opening poster having a severely atypical lesion versus melanoma in situ.  The differential diagnosis, however, was a stage 1a melanoma of 0.8mm in depth which is not melanoma in situ.

                     

                     

                    KnowThyself
                    Participant

                      Thanks Janner,

                      Thank you for your reply, and you're right, better safe than sorry…

                      I do have one more question….. At what depth would they recommend a SLNB? I have read a few different answers depending on where I look, but some say above 1mm, and some say between .75 and 1mm….. And my differential diagnosis would be a .8…….Also, where the ear is a risky place to begin with, do you think a SLNB is something I should push for? They have not suggested it yet, however I have yet to see an oncologist or melanoma specialist throughout all of this, I have seen an ear nose and throat doc for my first excision, and a plastic and hand doc for the wide excision… (the plastic and hand doc being moreso competent about the situation, but still, melanoma not being an area of his expertise)….. I have been showing a lot of symptoms lately, so many different things going on, between neurological, abdominal, and just general sickness (severe headaches, dizzy spells, trouble with concentration, modd swings, severe bloating and gurth, intestinal issues, even came down with a "beta-strep" infection in my throat, with a fever, enlarged lymph nodes (hae since gone back down)……..Basically, I am a mess…. I feel there are other things going on in my body aside from this melanoma, but not sure where to start…. Should I wait on asking about SLNB? And maybe just get an MRI or something instead, to get a bigger -picture look?? Because even after they remove the rest of my ear, I'll still be worried….

                      KnowThyself
                      Participant

                        Thanks Janner,

                        Thank you for your reply, and you're right, better safe than sorry…

                        I do have one more question….. At what depth would they recommend a SLNB? I have read a few different answers depending on where I look, but some say above 1mm, and some say between .75 and 1mm….. And my differential diagnosis would be a .8…….Also, where the ear is a risky place to begin with, do you think a SLNB is something I should push for? They have not suggested it yet, however I have yet to see an oncologist or melanoma specialist throughout all of this, I have seen an ear nose and throat doc for my first excision, and a plastic and hand doc for the wide excision… (the plastic and hand doc being moreso competent about the situation, but still, melanoma not being an area of his expertise)….. I have been showing a lot of symptoms lately, so many different things going on, between neurological, abdominal, and just general sickness (severe headaches, dizzy spells, trouble with concentration, modd swings, severe bloating and gurth, intestinal issues, even came down with a "beta-strep" infection in my throat, with a fever, enlarged lymph nodes (hae since gone back down)……..Basically, I am a mess…. I feel there are other things going on in my body aside from this melanoma, but not sure where to start…. Should I wait on asking about SLNB? And maybe just get an MRI or something instead, to get a bigger -picture look?? Because even after they remove the rest of my ear, I'll still be worried….

                        KnowThyself
                        Participant

                          Thanks Janner,

                          Thank you for your reply, and you're right, better safe than sorry…

                          I do have one more question….. At what depth would they recommend a SLNB? I have read a few different answers depending on where I look, but some say above 1mm, and some say between .75 and 1mm….. And my differential diagnosis would be a .8…….Also, where the ear is a risky place to begin with, do you think a SLNB is something I should push for? They have not suggested it yet, however I have yet to see an oncologist or melanoma specialist throughout all of this, I have seen an ear nose and throat doc for my first excision, and a plastic and hand doc for the wide excision… (the plastic and hand doc being moreso competent about the situation, but still, melanoma not being an area of his expertise)….. I have been showing a lot of symptoms lately, so many different things going on, between neurological, abdominal, and just general sickness (severe headaches, dizzy spells, trouble with concentration, modd swings, severe bloating and gurth, intestinal issues, even came down with a "beta-strep" infection in my throat, with a fever, enlarged lymph nodes (hae since gone back down)……..Basically, I am a mess…. I feel there are other things going on in my body aside from this melanoma, but not sure where to start…. Should I wait on asking about SLNB? And maybe just get an MRI or something instead, to get a bigger -picture look?? Because even after they remove the rest of my ear, I'll still be worried….

                          KnowThyself
                          Participant

                            ……and I hate to have to keep cost in mind, but Ive read a SLNB is wildly expensive, anyone know what Id be looking at for an MRI, or something of that sort?

                            KnowThyself
                            Participant

                              ……and I hate to have to keep cost in mind, but Ive read a SLNB is wildly expensive, anyone know what Id be looking at for an MRI, or something of that sort?

                              KnowThyself
                              Participant

                                ……and I hate to have to keep cost in mind, but Ive read a SLNB is wildly expensive, anyone know what Id be looking at for an MRI, or something of that sort?

                                KnowThyself
                                Participant

                                  ……oh and ALSO, they gave me this depth (.8mm) AFTER the biopsy, excision, and wide excision…. so the lesion had already been biopsied and removed once before they got their sample…. Is there any way it could have been deeper to begin with? Dont know why they never gave me a depth before in my other path reports, but in the path report before this one, they gave me "boderline level II stage pt1A" as well…… So between all the path reports, seems that they believe it MAY be level II, stage pt1A with a depth of .8…….  (it doesnt specify if this depth is 'thickness' I know they dont usually go by breslow depth anymore, but is depth and thickness the same?)…….I guess it doesnt matter much by now, either way Im going to have the rest removed, but I'm just trying to look at it from every angle to see if this should warrant at least an MRI….. I read more into the SLNB too, and they DONT recommend it for patients who have already had a WLE, because it would alter the drainage pattern…..and they dont recommend it on head/neck patients because there are too many nodes and basins that it could possible drain into….. So….. looks like my only other option if I feel the need to look deeper into it would be an MRI…… I hate this :'( 

                                  KnowThyself
                                  Participant

                                    ……oh and ALSO, they gave me this depth (.8mm) AFTER the biopsy, excision, and wide excision…. so the lesion had already been biopsied and removed once before they got their sample…. Is there any way it could have been deeper to begin with? Dont know why they never gave me a depth before in my other path reports, but in the path report before this one, they gave me "boderline level II stage pt1A" as well…… So between all the path reports, seems that they believe it MAY be level II, stage pt1A with a depth of .8…….  (it doesnt specify if this depth is 'thickness' I know they dont usually go by breslow depth anymore, but is depth and thickness the same?)…….I guess it doesnt matter much by now, either way Im going to have the rest removed, but I'm just trying to look at it from every angle to see if this should warrant at least an MRI….. I read more into the SLNB too, and they DONT recommend it for patients who have already had a WLE, because it would alter the drainage pattern…..and they dont recommend it on head/neck patients because there are too many nodes and basins that it could possible drain into….. So….. looks like my only other option if I feel the need to look deeper into it would be an MRI…… I hate this :'( 

                                    KnowThyself
                                    Participant

                                      ……oh and ALSO, they gave me this depth (.8mm) AFTER the biopsy, excision, and wide excision…. so the lesion had already been biopsied and removed once before they got their sample…. Is there any way it could have been deeper to begin with? Dont know why they never gave me a depth before in my other path reports, but in the path report before this one, they gave me "boderline level II stage pt1A" as well…… So between all the path reports, seems that they believe it MAY be level II, stage pt1A with a depth of .8…….  (it doesnt specify if this depth is 'thickness' I know they dont usually go by breslow depth anymore, but is depth and thickness the same?)…….I guess it doesnt matter much by now, either way Im going to have the rest removed, but I'm just trying to look at it from every angle to see if this should warrant at least an MRI….. I read more into the SLNB too, and they DONT recommend it for patients who have already had a WLE, because it would alter the drainage pattern…..and they dont recommend it on head/neck patients because there are too many nodes and basins that it could possible drain into….. So….. looks like my only other option if I feel the need to look deeper into it would be an MRI…… I hate this :'( 

                                      Janner
                                      Participant

                                        Because your lesion is stage IA (no mitosis), they don't usually do a SNB.  If this was stage IB, it would be questionable given the depth.  However, more places are doing the SNB for stage IB lesions regardless of depth.  In addition, it typically needs to be done PRIOR to the WLE.  There's little question about where the ear drains to, but you may not get the original sentinel node that you might have been prior to the WLE.

                                        Janner
                                        Participant

                                          Because your lesion is stage IA (no mitosis), they don't usually do a SNB.  If this was stage IB, it would be questionable given the depth.  However, more places are doing the SNB for stage IB lesions regardless of depth.  In addition, it typically needs to be done PRIOR to the WLE.  There's little question about where the ear drains to, but you may not get the original sentinel node that you might have been prior to the WLE.

                                          Janner
                                          Participant

                                            Because your lesion is stage IA (no mitosis), they don't usually do a SNB.  If this was stage IB, it would be questionable given the depth.  However, more places are doing the SNB for stage IB lesions regardless of depth.  In addition, it typically needs to be done PRIOR to the WLE.  There's little question about where the ear drains to, but you may not get the original sentinel node that you might have been prior to the WLE.

                                            Janner
                                            Participant

                                              I know the lesion was stage IA, but he is asking about the residual neoplasm and asking if that is cancer or benign.   I was trying to explain the difference or similarities between the two and what is typically done with each.

                                              I've never had it clarified to me what should be done if a stage I lesion is removed but there is residual in situ at the margins.  Do you take stage I  or in situ margins for the WLE.  I've seen posts on here that seem to go both ways, but this is still unclear in my mind as to what makes sense.  For me, there is no question on what I'd do if I were the original poster.  He doesn't have clear enough margins from the removed melanoma to be safe.  He doesn't have the 1 cm (stage I) or 5mm (in situ / severely atypical) minimum margins from cancerous (or nearly) cells.  Being without insurance certainly makes us question things which might be "optional" and I understand the reason he asked the question.  But this wouldn't be optional in my book.

                                              Thanks for raising the point, however, because you are right, I didn't address the stage I issue and wouldn't want to add any confusion.

                                              Best wishes,

                                              Janner

                                              Janner
                                              Participant

                                                I know the lesion was stage IA, but he is asking about the residual neoplasm and asking if that is cancer or benign.   I was trying to explain the difference or similarities between the two and what is typically done with each.

                                                I've never had it clarified to me what should be done if a stage I lesion is removed but there is residual in situ at the margins.  Do you take stage I  or in situ margins for the WLE.  I've seen posts on here that seem to go both ways, but this is still unclear in my mind as to what makes sense.  For me, there is no question on what I'd do if I were the original poster.  He doesn't have clear enough margins from the removed melanoma to be safe.  He doesn't have the 1 cm (stage I) or 5mm (in situ / severely atypical) minimum margins from cancerous (or nearly) cells.  Being without insurance certainly makes us question things which might be "optional" and I understand the reason he asked the question.  But this wouldn't be optional in my book.

                                                Thanks for raising the point, however, because you are right, I didn't address the stage I issue and wouldn't want to add any confusion.

                                                Best wishes,

                                                Janner

                                                Janner
                                                Participant

                                                  I know the lesion was stage IA, but he is asking about the residual neoplasm and asking if that is cancer or benign.   I was trying to explain the difference or similarities between the two and what is typically done with each.

                                                  I've never had it clarified to me what should be done if a stage I lesion is removed but there is residual in situ at the margins.  Do you take stage I  or in situ margins for the WLE.  I've seen posts on here that seem to go both ways, but this is still unclear in my mind as to what makes sense.  For me, there is no question on what I'd do if I were the original poster.  He doesn't have clear enough margins from the removed melanoma to be safe.  He doesn't have the 1 cm (stage I) or 5mm (in situ / severely atypical) minimum margins from cancerous (or nearly) cells.  Being without insurance certainly makes us question things which might be "optional" and I understand the reason he asked the question.  But this wouldn't be optional in my book.

                                                  Thanks for raising the point, however, because you are right, I didn't address the stage I issue and wouldn't want to add any confusion.

                                                  Best wishes,

                                                  Janner

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