Braf/mek/staging

Hello there :o)

My farher was diagnosed with III C stage on april 2018. He had reoccurence after 3 months after first melanoma removal. He was on Keytruda (similar to Opdivo) for 6 dosages, but it didn’t work for him, too. Imunotherapy failed.. We were absolutely desperate, because his skin arround initial melanoma scar was full of big tumors (tenis and golf balls) .. Cancer was spreading.. Into his lungs.. He was laying in hospital, lost 30 kg.. I was crying everyday, had feeling he could die everyday there.. He looked soo poor.. So weak.. UNTIL…. They put him on TAF/MEK treatment..
From about 40 skin ball tumors, he has only two of them now!!! His lungs are clear!! His lymph node shrinked, and is clear now..
It’s a kind of a mirracle! He is BRAF positive.. And it worked perfectly..
I wish you had so great response to this treatment, too!!
Wish you all the best!
Hope sharing our story will fill your heart with hope.. My father is 68 yo.

I was diagnosied with recurrance melanoma stage 4 2 years ago and surgury was not possible i was told ,large tumor in neck. I was put on Roche combo and was on just 11 days had bad skin reaction so stopped treatment. Over next 3 months tumour shrank away and PET SCAN then showed NED.I then started Novartis combo and have erytha nodosum like leasion as side effect that clear up when off Dabrafeneb and Meck. So am off and on drugs every 3 weeks even though i am on lowest dose.Iam still NED 21 months later. I hope this gives you hope as even at low doses and sometimes short time frame they can work wonders.Sending love and prayers to you,try to keep positive outlook i know that has helped me i hope it will help you as well.