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BRAF Gene

› Forums › General Melanoma Community › BRAF Gene

  • Post
    • February 27, 2012 at 8:08 pm
    Kimberly Duncan Watts
    Participant
      Another question already! I was told I do not qualify for zelboraf because my BRAF gene is “abnormal”. Again, that happen to anybody else?

      Another question already! I was told I do not qualify for zelboraf because my BRAF gene is “abnormal”. Again, that happen to anybody else?

    Viewing 5 reply threads
    • Replies
        • February 27, 2012 at 8:26 pm
        boot2aboot
        Participant

          what do you mean 'abnormal'…give us the results…is it braf v600e or k? or wild type?

          did you get tested for other mutations like ckit?

          what have you tried so far?

          boots

          • February 27, 2012 at 8:26 pm
          boot2aboot
          Participant

            what do you mean 'abnormal'…give us the results…is it braf v600e or k? or wild type?

            did you get tested for other mutations like ckit?

            what have you tried so far?

            boots

            • February 27, 2012 at 8:26 pm
            boot2aboot
            Participant

              what do you mean 'abnormal'…give us the results…is it braf v600e or k? or wild type?

              did you get tested for other mutations like ckit?

              what have you tried so far?

              boots

              • February 27, 2012 at 10:07 pm
              aldakota22
              Participant

                Don't think they  meant abnormal.Braf is either positive or negative.Zelboraf  will only work on patients who  have tested positive.If you are negative it is not a course of treatment.Find another course of treatment.Prayers go with you.                      Al

                  • February 28, 2012 at 12:24 pm
                  Kimberly Duncan Watts
                  Participant
                    “abnormal” is the term they used. Im positive for the gene mutation, but it isn’t the same as everybody else’s. My onc did his very best at the big symposium last fall to find a center that had run across, but, alas, no one had seen it before…. I will ask again Friday.
                    • February 28, 2012 at 3:16 pm
                    kylez
                    Participant

                      I have a BRAF mutation, G466E. Maybe that would also be what your doc calls 'abnormal'. It doesn't qualify me for any of the BRAF inhibitors, which all target the V600E or V600K mutations as far as I know.

                      • February 28, 2012 at 6:27 pm
                      Kimberly Duncan Watts
                      Participant
                        I will take that piece of info with me when I see onc. On Friday. Thanks very much!
                        • February 28, 2012 at 6:27 pm
                        Kimberly Duncan Watts
                        Participant
                          I will take that piece of info with me when I see onc. On Friday. Thanks very much!
                          • February 28, 2012 at 6:27 pm
                          Kimberly Duncan Watts
                          Participant
                            I will take that piece of info with me when I see onc. On Friday. Thanks very much!
                            • February 28, 2012 at 3:16 pm
                            kylez
                            Participant

                              I have a BRAF mutation, G466E. Maybe that would also be what your doc calls 'abnormal'. It doesn't qualify me for any of the BRAF inhibitors, which all target the V600E or V600K mutations as far as I know.

                              • February 28, 2012 at 3:16 pm
                              kylez
                              Participant

                                I have a BRAF mutation, G466E. Maybe that would also be what your doc calls 'abnormal'. It doesn't qualify me for any of the BRAF inhibitors, which all target the V600E or V600K mutations as far as I know.

                                • February 28, 2012 at 12:24 pm
                                Kimberly Duncan Watts
                                Participant
                                  “abnormal” is the term they used. Im positive for the gene mutation, but it isn’t the same as everybody else’s. My onc did his very best at the big symposium last fall to find a center that had run across, but, alas, no one had seen it before…. I will ask again Friday.
                                  • February 28, 2012 at 12:24 pm
                                  Kimberly Duncan Watts
                                  Participant
                                    “abnormal” is the term they used. Im positive for the gene mutation, but it isn’t the same as everybody else’s. My onc did his very best at the big symposium last fall to find a center that had run across, but, alas, no one had seen it before…. I will ask again Friday.
                                  • February 27, 2012 at 10:07 pm
                                  aldakota22
                                  Participant

                                    Don't think they  meant abnormal.Braf is either positive or negative.Zelboraf  will only work on patients who  have tested positive.If you are negative it is not a course of treatment.Find another course of treatment.Prayers go with you.                      Al

                                    • February 27, 2012 at 10:07 pm
                                    aldakota22
                                    Participant

                                      Don't think they  meant abnormal.Braf is either positive or negative.Zelboraf  will only work on patients who  have tested positive.If you are negative it is not a course of treatment.Find another course of treatment.Prayers go with you.                      Al

                                  Viewing 5 reply threads
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