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- June 3, 2015 at 10:41 pm
Hello,
I have been on the Tafinlar/Mekinist (Dabrafenib/Trametinib) combo for about 6 weeks now. When I began I experienced some mild joint aches but they went away after only a week. After that I felt great!
Well they have returned and the intensity has increased. I wake up feeling achy all over my body and it doesn't go away unless I take 2 ibuprofen (400mg total). I have to do this 2-3 times per day to keep it away. I don't like taking this much ibuprofen.
Has anyone else experienced this and do you have any suggestions for managing it? Dose reduction? Drug holiday, heat, etc??
Thanks
Mark
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