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Bloodwork results after nivo/ipi 2nd infusion
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Bloodwork results after nivo/ipi 2nd infusion

› Forums › General Melanoma Community › Bloodwork results after nivo/ipi 2nd infusion

  • Post
    • April 2, 2020 at 3:31 am
    Beany
    Participant
      Hello everyone,
      I am just about to get my third infusion and here are the blood test results. Could you please tell me what you think of these levels especially AST, ALT, and LDH/LD.
      I am not sure why LDH is not registered whereas LD is. I will ask the doctor soon.
      AST (GOT) 39
      ALT(GPT) 60
      LD(IFCC) 235
      Sincere thanks in advance
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    • Replies
        • April 2, 2020 at 3:27 pm
        ed williams
        Participant
          The basic answer is blood work has a range of values and if you fall within the normal range like AST and ALT then nothing to worry about. Now, each immune related side effect that can develop because of using the combination of ipi/nivo or Pd-1 drugs alone, the oncologist or nursing staff will look at table developed by drug companies or oncology community as to what grade of side effect the patient is experiencing and each side effect has different criteria. An example for colitis, it is based on how many times above normal you are going to bathroom each day and they use that information to grade how severe the diarrhea is and based on the established table they treat by holding back next treatment or maybe they have to add intervention of steroids. Here is a link that gives all the possible side effects and each one has a table with how to establish the appropriate grade of problem and then how to best manage the problem. Your blood work looks pretty normal to me but then again I am not a Dr. https://ascopubs.org/doi/10.1200/JCO.2017.77.6385
            • April 2, 2020 at 4:02 pm
            Beany
            Participant
              Hello Ed,
              Thank you replying, and thanks for the link. Very useful.
              Sincere thanks,
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