› Forums › General Melanoma Community › Baylor Sammon Yervoy (Ipilimumab) vs. OPDIVO (Nivolumab) Phase III Clinical Trial
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Speedster.
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- May 9, 2015 at 6:19 pm
Back on April 14, 2015, I was patient #1 for the Yervoy (Ipilimumab) vs. OPDIVO (Nivolumab) Phase III clinical trial for Stage III metastatic melanoma patients – resected tumors, No Evidence of Disease.
Who else is in and what are you experiencing? I"m super pleased with the entire team there having had a less that stellar experince at MD Anderson, which is an amazing resource none the less. .
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- May 11, 2015 at 8:04 pm
My husband really liked Baylor and preferred it over UT Southwestern. The staff is very friendly and Dr. Cowey made us feel comfortable, answered our questions, and we just knew it was where he wanted to seek care.
He is Stage 3b although it's debatable if he was really 3a or 3b however Dr. Cowey wants to be more aggressive – we are going with 3b nonetheless. He hasn't started it yet and was just filling out the paperwork yesterday. He's nervous about the side effects. I'm curious to know what you've been experiencing. How often do you go? I wish you all the best and would love to stay in touch along the way.
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- May 14, 2015 at 5:15 pm
I've had three treatmetns, which means I've gotten the actual medication twice as part of the double-blind study. On Monay (5/11), when I was to get my fourth, I was unable to get it as my liver function was out of bounds. Having tested it again to day, it's gone even further, which is a real concern and puts me on indefinite hold.
So, yes, toxicity is a reall issue and I've had a long list of minor and a little more severe issues inclunding a bad reaction to Doxycycline that cause a terrible rash and high fever, another rash that makes me crazy at night, headaches, chills, sweats, joint and body aches…). Yet I'm confiendt this is the right course as Interferon is horrid and has littiel curative effect. Doing nothing is high rish as melanoma does not sleep.
I hope my liver recovers soon and I can get rolling again.
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- May 25, 2015 at 3:33 am
As of today's blood test, my liver is almost back to normal after 10 days of Predisone steroids. We discovered today my pancreas is stressed, yet within a Grade I toxicity event, so I can be treated this Tuesady, May 26. It will be interesting to see how I tolerate my third treatment assuming I'm on the ipi leg of the trial. Hopefully my liver, pancreas and skin tolerate it well.
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- May 25, 2015 at 10:00 pm
So glad to hear you are able to continue! My husband submitted all the paperwork and now we are waiting to have his full day of testing and then we're off! Let us know if you are able to continue – here's to hoping the pancreas settles down. Do you think you are on the ipi leg based off symptoms?
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- June 2, 2015 at 12:31 am
As my liver has recovered and the seroids are being tapered down, I'll be treated again next Monday June 8, then June 15 and June 22. I pray my system tolderates what I beleive will be my last high dose of Ipilumumab if I"m on that leg of the trail, yet that's not certain.
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- June 2, 2015 at 12:31 am
As my liver has recovered and the seroids are being tapered down, I'll be treated again next Monday June 8, then June 15 and June 22. I pray my system tolderates what I beleive will be my last high dose of Ipilumumab if I"m on that leg of the trail, yet that's not certain.
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- June 2, 2015 at 12:31 am
As my liver has recovered and the seroids are being tapered down, I'll be treated again next Monday June 8, then June 15 and June 22. I pray my system tolderates what I beleive will be my last high dose of Ipilumumab if I"m on that leg of the trail, yet that's not certain.
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- May 25, 2015 at 10:00 pm
So glad to hear you are able to continue! My husband submitted all the paperwork and now we are waiting to have his full day of testing and then we're off! Let us know if you are able to continue – here's to hoping the pancreas settles down. Do you think you are on the ipi leg based off symptoms?
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- May 25, 2015 at 10:00 pm
So glad to hear you are able to continue! My husband submitted all the paperwork and now we are waiting to have his full day of testing and then we're off! Let us know if you are able to continue – here's to hoping the pancreas settles down. Do you think you are on the ipi leg based off symptoms?
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- May 25, 2015 at 3:33 am
As of today's blood test, my liver is almost back to normal after 10 days of Predisone steroids. We discovered today my pancreas is stressed, yet within a Grade I toxicity event, so I can be treated this Tuesady, May 26. It will be interesting to see how I tolerate my third treatment assuming I'm on the ipi leg of the trial. Hopefully my liver, pancreas and skin tolerate it well.
-
- May 25, 2015 at 3:33 am
As of today's blood test, my liver is almost back to normal after 10 days of Predisone steroids. We discovered today my pancreas is stressed, yet within a Grade I toxicity event, so I can be treated this Tuesady, May 26. It will be interesting to see how I tolerate my third treatment assuming I'm on the ipi leg of the trial. Hopefully my liver, pancreas and skin tolerate it well.
-
- May 14, 2015 at 5:15 pm
I've had three treatmetns, which means I've gotten the actual medication twice as part of the double-blind study. On Monay (5/11), when I was to get my fourth, I was unable to get it as my liver function was out of bounds. Having tested it again to day, it's gone even further, which is a real concern and puts me on indefinite hold.
So, yes, toxicity is a reall issue and I've had a long list of minor and a little more severe issues inclunding a bad reaction to Doxycycline that cause a terrible rash and high fever, another rash that makes me crazy at night, headaches, chills, sweats, joint and body aches…). Yet I'm confiendt this is the right course as Interferon is horrid and has littiel curative effect. Doing nothing is high rish as melanoma does not sleep.
I hope my liver recovers soon and I can get rolling again.
-
- May 14, 2015 at 5:15 pm
I've had three treatmetns, which means I've gotten the actual medication twice as part of the double-blind study. On Monay (5/11), when I was to get my fourth, I was unable to get it as my liver function was out of bounds. Having tested it again to day, it's gone even further, which is a real concern and puts me on indefinite hold.
So, yes, toxicity is a reall issue and I've had a long list of minor and a little more severe issues inclunding a bad reaction to Doxycycline that cause a terrible rash and high fever, another rash that makes me crazy at night, headaches, chills, sweats, joint and body aches…). Yet I'm confiendt this is the right course as Interferon is horrid and has littiel curative effect. Doing nothing is high rish as melanoma does not sleep.
I hope my liver recovers soon and I can get rolling again.
-
- May 11, 2015 at 8:04 pm
My husband really liked Baylor and preferred it over UT Southwestern. The staff is very friendly and Dr. Cowey made us feel comfortable, answered our questions, and we just knew it was where he wanted to seek care.
He is Stage 3b although it's debatable if he was really 3a or 3b however Dr. Cowey wants to be more aggressive – we are going with 3b nonetheless. He hasn't started it yet and was just filling out the paperwork yesterday. He's nervous about the side effects. I'm curious to know what you've been experiencing. How often do you go? I wish you all the best and would love to stay in touch along the way.
-
- May 11, 2015 at 8:04 pm
My husband really liked Baylor and preferred it over UT Southwestern. The staff is very friendly and Dr. Cowey made us feel comfortable, answered our questions, and we just knew it was where he wanted to seek care.
He is Stage 3b although it's debatable if he was really 3a or 3b however Dr. Cowey wants to be more aggressive – we are going with 3b nonetheless. He hasn't started it yet and was just filling out the paperwork yesterday. He's nervous about the side effects. I'm curious to know what you've been experiencing. How often do you go? I wish you all the best and would love to stay in touch along the way.
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