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Re: IL-21 vs DTIC – thoughts please
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Re: IL-21 vs DTIC – thoughts please

› Forums › General Melanoma Community › IL-21 vs DTIC – thoughts please › Re: IL-21 vs DTIC – thoughts please

    • August 14, 2010 at 12:01 am
    Kim K
    Participant

      I think you have a solid plan.  The reason I did IL-2 was because of the chance for prolonged remission if you were a complete responder.  DTIC has similar numbers of complete responders but their long term response wasn't as durable.  Yes the side effects are nasty for IL-2, but once completed you rapidly recover.  In addition, you are aggressivley treated for those side effects in the ICU or similar unit.  It is short term.  You respond or you don't.

      It sounded like you folks already went down the IL-2 path with your post.  If he didn't respond then, then don't waste your time with it.  IPI is a good alternative.  You have a good, well thought out plan.  The only problem with the inhibitors though is that they don't readily cross the blood brain barrier, and need to be taken indefinately.  Yes, they also have side effects ex. joint pain.

      You are doing a great job navigating the waters.  There never is one best treatment.  You decide what is best for you and NEVER look back.  You both have to buy into your treatment, then give it time to work.  I hope his disease isn't rapidly progressive.

      Best of luck,

      Kim K – stage IV, NED 1 mos.

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