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Viagra linked to melanoma??

Forums General Melanoma Community Viagra linked to melanoma??

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      shanemcdonald99
      Participant

      you better stop taking it then Ginger !

      lol

       

      shane

       

      had some fatigue and weakness this week from Yervoy, but not too bad.

      Next week is infusion 2

      shanemcdonald99
      Participant

      you better stop taking it then Ginger !

      lol

       

      shane

       

      had some fatigue and weakness this week from Yervoy, but not too bad.

      Next week is infusion 2

        Ginger8888
        Participant

        Haha!! I don't need it..lol..My first infusion of Yervoy was last week..Blood work tomorrow and next treatment is July 3..Good luck

        Ginger8888
        Participant

        Haha!! I don't need it..lol..My first infusion of Yervoy was last week..Blood work tomorrow and next treatment is July 3..Good luck

        Ginger8888
        Participant

        Haha!! I don't need it..lol..My first infusion of Yervoy was last week..Blood work tomorrow and next treatment is July 3..Good luck

        JamesH
        Participant

        Melanoma is very nasty. Many of you know this much better than I do.  This really is not a joke!

        Melanoma cancer may just be the start of what is to come for Vigra!!!  

        JamesH
        Participant

        Melanoma is very nasty. Many of you know this much better than I do.  This really is not a joke!

        Melanoma cancer may just be the start of what is to come for Vigra!!!  

        JamesH
        Participant

        Melanoma is very nasty. Many of you know this much better than I do.  This really is not a joke!

        Melanoma cancer may just be the start of what is to come for Vigra!!!  

      shanemcdonald99
      Participant

      you better stop taking it then Ginger !

      lol

       

      shane

       

      had some fatigue and weakness this week from Yervoy, but not too bad.

      Next week is infusion 2

      joelcairo
      Participant

      Not sure what to make of this study. Unfortunately I can only see the abstract. It seems sound, but I wonder if the researchers were really able to account for confounding factors, such as Viagra use being generally associated with increasing age and poor blood circulation.

      Also grouping patients into two categories of "ever used" and "never used" seems overly crude. It would be better to see a graph demonstrating a trend of increased use leading to increased risk. Perhaps that would require a larger study.

      BTW, I'm troubled mainly because Viagra has also been associated with some cancer protective activities such as reducing inflammation and reducing immunosuppression. It may be that the negatives outweigh the positives.

       

      joelcairo
      Participant

      Not sure what to make of this study. Unfortunately I can only see the abstract. It seems sound, but I wonder if the researchers were really able to account for confounding factors, such as Viagra use being generally associated with increasing age and poor blood circulation.

      Also grouping patients into two categories of "ever used" and "never used" seems overly crude. It would be better to see a graph demonstrating a trend of increased use leading to increased risk. Perhaps that would require a larger study.

      BTW, I'm troubled mainly because Viagra has also been associated with some cancer protective activities such as reducing inflammation and reducing immunosuppression. It may be that the negatives outweigh the positives.

       

        Ginger8888
        Participant

        Something to think and ask about, not sure where they're going with it, i just seen this on one of my facebook pages and thought i'd share it..I hope it's helpful..

        Ginger8888
        Participant

        Something to think and ask about, not sure where they're going with it, i just seen this on one of my facebook pages and thought i'd share it..I hope it's helpful..

        Ginger8888
        Participant

        Something to think and ask about, not sure where they're going with it, i just seen this on one of my facebook pages and thought i'd share it..I hope it's helpful..

        JamesH
        Participant

        Joel. You would be surprised how much actually went into the study to analyze variables such as those you mention.  You can read more about the actual study here:  JAMA Harvard Viagra Melanoma Study

        If you would like a toned down version…  The study took into account many outside factors including family history, uv exposure and other variables. 

        Viagra, Levitra and Cialis are designed to block/ inhibit PDE5 which otherwise would restrict blood flow to the penis. Maybe what happens is that PDE5 also slows down blood flow to melanoma cells that would otherwise never spread?  It is possible…  The study shows an 84% increase in men's risk of melanoma. It was a study from Harvard… Not too shabby…  It included over 25,000 men… Certainly more than a handful… 

        It is told that sunburns can double your melanoma risks.  IT WAS NOT ON VIAGRA's LABEL!

        If you know anyone who this might apply to, check out this:  http://www.viagramelanomaattorney.com

        JamesH
        Participant

        Joel. You would be surprised how much actually went into the study to analyze variables such as those you mention.  You can read more about the actual study here:  JAMA Harvard Viagra Melanoma Study

        If you would like a toned down version…  The study took into account many outside factors including family history, uv exposure and other variables. 

        Viagra, Levitra and Cialis are designed to block/ inhibit PDE5 which otherwise would restrict blood flow to the penis. Maybe what happens is that PDE5 also slows down blood flow to melanoma cells that would otherwise never spread?  It is possible…  The study shows an 84% increase in men's risk of melanoma. It was a study from Harvard… Not too shabby…  It included over 25,000 men… Certainly more than a handful… 

        It is told that sunburns can double your melanoma risks.  IT WAS NOT ON VIAGRA's LABEL!

        If you know anyone who this might apply to, check out this:  http://www.viagramelanomaattorney.com

        JamesH
        Participant

        Joel. You would be surprised how much actually went into the study to analyze variables such as those you mention.  You can read more about the actual study here:  JAMA Harvard Viagra Melanoma Study

        If you would like a toned down version…  The study took into account many outside factors including family history, uv exposure and other variables. 

        Viagra, Levitra and Cialis are designed to block/ inhibit PDE5 which otherwise would restrict blood flow to the penis. Maybe what happens is that PDE5 also slows down blood flow to melanoma cells that would otherwise never spread?  It is possible…  The study shows an 84% increase in men's risk of melanoma. It was a study from Harvard… Not too shabby…  It included over 25,000 men… Certainly more than a handful… 

        It is told that sunburns can double your melanoma risks.  IT WAS NOT ON VIAGRA's LABEL!

        If you know anyone who this might apply to, check out this:  http://www.viagramelanomaattorney.com

      joelcairo
      Participant

      Not sure what to make of this study. Unfortunately I can only see the abstract. It seems sound, but I wonder if the researchers were really able to account for confounding factors, such as Viagra use being generally associated with increasing age and poor blood circulation.

      Also grouping patients into two categories of "ever used" and "never used" seems overly crude. It would be better to see a graph demonstrating a trend of increased use leading to increased risk. Perhaps that would require a larger study.

      BTW, I'm troubled mainly because Viagra has also been associated with some cancer protective activities such as reducing inflammation and reducing immunosuppression. It may be that the negatives outweigh the positives.

       

      Janner
      Participant

      Personally, I think it's a flawed study to start with.  THE most likely population to get melanoma is older men (even before Viagra).  The most likely population to use Viagra is older men.  Correlation is not cause.

      Janner
      Participant

      Personally, I think it's a flawed study to start with.  THE most likely population to get melanoma is older men (even before Viagra).  The most likely population to use Viagra is older men.  Correlation is not cause.

      Janner
      Participant

      Personally, I think it's a flawed study to start with.  THE most likely population to get melanoma is older men (even before Viagra).  The most likely population to use Viagra is older men.  Correlation is not cause.

        Ginger8888
        Participant

        Good point.. I don't anything about Viagra and am new to the melanoma world so i'm still learning new things everyday..

        Ginger8888
        Participant

        Good point.. I don't anything about Viagra and am new to the melanoma world so i'm still learning new things everyday..

        Ginger8888
        Participant

        Good point.. I don't anything about Viagra and am new to the melanoma world so i'm still learning new things everyday..

        WOStavelot
        Participant

        Personally, I wonder if those wrting here have read the study. Not only does it address all the concerns voiced here, which are valid, but for me it fits perfectly into all the current evidence coming out of Molecular Biology that relates directly to melanoma. The legal aspects of this don't concern me, but I doubt that was an issue when these investigators formulated their hypothesis.

        The "numbers" are more than adequate when one reads the report. "Big numbers," which this study has, aren't the goal nor the final determinant of value in medical research : it's usually investigator insight.

        When Alexander Breslow, (I had the pleasure and true opportunity of being one of his students), reported in 1969 on the importance of thickness in cutaneous melanomas, he did so quite humbly, based on 98 patients at GW. Not a huge number when compared with meta-analyses commonly seen today. But his results remain one of the guiding lights of Staging and Prognosis in melanoma care. By comparison, many huge meta-analyses have come and gone with the wind. But the statistics in his "little study" were good and supported his claims that cutaneous melanomas less than 0.76 mm thick had neither recurrence nor metastases,and that one could use thickness to predict outcome.

        The numbers, and conclusions as stated in this study on Viagra and melanoma are good as well.

        Don't be scared away by all the biomolecular terms for how this medicine, and melanoma initiation "works." It doesn't explain, or try to explain, everything about these relationships. But it's a good study. It teaches more about making inroads into countering melanoma.

        Does an attorney you know take Viagra? One could hope so …

        joelcairo
        Participant

        Thank you for linking to the full study under discussion. It's true that the health status of the participants was considered, but excluding major chonic diseases does not completely account for what must be a powerful correlation between Viagra use and generally poorer health by some measures.

        Also, in some studies Viagra has been shown to reduce inflammation and reduce inflammation-related immunosppression. So it's possible there could be two countervailing effects at work here.

         

        joelcairo
        Participant

        Thank you for linking to the full study under discussion. It's true that the health status of the participants was considered, but excluding major chonic diseases does not completely account for what must be a powerful correlation between Viagra use and generally poorer health by some measures.

        Also, in some studies Viagra has been shown to reduce inflammation and reduce inflammation-related immunosppression. So it's possible there could be two countervailing effects at work here.

         

        joelcairo
        Participant

        Thank you for linking to the full study under discussion. It's true that the health status of the participants was considered, but excluding major chonic diseases does not completely account for what must be a powerful correlation between Viagra use and generally poorer health by some measures.

        Also, in some studies Viagra has been shown to reduce inflammation and reduce inflammation-related immunosppression. So it's possible there could be two countervailing effects at work here.

         

        WOStavelot
        Participant

        Personally, I wonder if those wrting here have read the study. Not only does it address all the concerns voiced here, which are valid, but for me it fits perfectly into all the current evidence coming out of Molecular Biology that relates directly to melanoma. The legal aspects of this don't concern me, but I doubt that was an issue when these investigators formulated their hypothesis.

        The "numbers" are more than adequate when one reads the report. "Big numbers," which this study has, aren't the goal nor the final determinant of value in medical research : it's usually investigator insight.

        When Alexander Breslow, (I had the pleasure and true opportunity of being one of his students), reported in 1969 on the importance of thickness in cutaneous melanomas, he did so quite humbly, based on 98 patients at GW. Not a huge number when compared with meta-analyses commonly seen today. But his results remain one of the guiding lights of Staging and Prognosis in melanoma care. By comparison, many huge meta-analyses have come and gone with the wind. But the statistics in his "little study" were good and supported his claims that cutaneous melanomas less than 0.76 mm thick had neither recurrence nor metastases,and that one could use thickness to predict outcome.

        The numbers, and conclusions as stated in this study on Viagra and melanoma are good as well.

        Don't be scared away by all the biomolecular terms for how this medicine, and melanoma initiation "works." It doesn't explain, or try to explain, everything about these relationships. But it's a good study. It teaches more about making inroads into countering melanoma.

        Does an attorney you know take Viagra? One could hope so …

        WOStavelot
        Participant

        Personally, I wonder if those wrting here have read the study. Not only does it address all the concerns voiced here, which are valid, but for me it fits perfectly into all the current evidence coming out of Molecular Biology that relates directly to melanoma. The legal aspects of this don't concern me, but I doubt that was an issue when these investigators formulated their hypothesis.

        The "numbers" are more than adequate when one reads the report. "Big numbers," which this study has, aren't the goal nor the final determinant of value in medical research : it's usually investigator insight.

        When Alexander Breslow, (I had the pleasure and true opportunity of being one of his students), reported in 1969 on the importance of thickness in cutaneous melanomas, he did so quite humbly, based on 98 patients at GW. Not a huge number when compared with meta-analyses commonly seen today. But his results remain one of the guiding lights of Staging and Prognosis in melanoma care. By comparison, many huge meta-analyses have come and gone with the wind. But the statistics in his "little study" were good and supported his claims that cutaneous melanomas less than 0.76 mm thick had neither recurrence nor metastases,and that one could use thickness to predict outcome.

        The numbers, and conclusions as stated in this study on Viagra and melanoma are good as well.

        Don't be scared away by all the biomolecular terms for how this medicine, and melanoma initiation "works." It doesn't explain, or try to explain, everything about these relationships. But it's a good study. It teaches more about making inroads into countering melanoma.

        Does an attorney you know take Viagra? One could hope so …

        JamesH
        Participant

        The same population…  84% increase in melanoma cancer from Viagra.  

        Harvard Medical School is not exactly the least among medical schools and institutions that study skin cancers.  Where did you graduate from?  84% is almost DOUBLE which is what many claim sunburn does to your risk for skin cancer.

        Do you also think the studies showing the suns harmful effects are also skewed? 

        JamesH
        Participant

        The same population…  84% increase in melanoma cancer from Viagra.  

        Harvard Medical School is not exactly the least among medical schools and institutions that study skin cancers.  Where did you graduate from?  84% is almost DOUBLE which is what many claim sunburn does to your risk for skin cancer.

        Do you also think the studies showing the suns harmful effects are also skewed? 

        JamesH
        Participant

        The same population…  84% increase in melanoma cancer from Viagra.  

        Harvard Medical School is not exactly the least among medical schools and institutions that study skin cancers.  Where did you graduate from?  84% is almost DOUBLE which is what many claim sunburn does to your risk for skin cancer.

        Do you also think the studies showing the suns harmful effects are also skewed? 

      JerryfromFauq
      Participant

      Also note that the article is for the purpose of trying to start a class action lawsuit for lawyers to collect millions of dollars!

        Ginger8888
        Participant

        No i'm sorry , i did not read the other attached articles..I really hate when those class acton suits show up…Personally i think they're just out for money..Again i'm sorry i should have looked into it further….

        Ginger8888
        Participant

        No i'm sorry , i did not read the other attached articles..I really hate when those class acton suits show up…Personally i think they're just out for money..Again i'm sorry i should have looked into it further….

        Ginger8888
        Participant

        No i'm sorry , i did not read the other attached articles..I really hate when those class acton suits show up…Personally i think they're just out for money..Again i'm sorry i should have looked into it further….

      JerryfromFauq
      Participant

      Also note that the article is for the purpose of trying to start a class action lawsuit for lawyers to collect millions of dollars!

      JerryfromFauq
      Participant

      Also note that the article is for the purpose of trying to start a class action lawsuit for lawyers to collect millions of dollars!

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