Stage IV
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Stage IV

› Forums › General Melanoma Community › Stage IV

  • Post
    • January 7, 2014 at 1:01 am
    Pathuttenga
    Participant

    My 34 year son was diagnosed two years ago

    large mole on torso surgically removed with lymph nodes under arm, one of 12 nodes infected

    radiation for 6 weeks then 12 months of interferon

    july 2013 MRI showed small brain lesion and 3 new tumors on torso and back

    radiation of total brain for 4 weeks plus 1 mega boost to exact spot

    12 weeks of yervoy

    good news brain MRI showed lesion gone

    bad news tumors on torso 2mm larger and also on liver and spleen and new tumor on thigh and side torso

    next step clinical trial – dr Laos at u of m has already closed his trial so have been recommended us to karmonas cancer at Wayne state

    waiting now for appt date

    Pat

Viewing 5 reply threads
  • Replies
      • January 7, 2014 at 3:06 am
      BrianP
      Participant

      Pat,

      Sorry for the latest bump in the road.  Has your son looked for PD-1 trials.  Seems like I've seen one or two lately that do allow for prior IPI treatments.  You may try to post on MIF and see if Catherine Poole knows of any.  She's a great resource for the latest and greatest on Nivo trials.  Good luck to you and your son.

      Brian

      • January 7, 2014 at 3:06 am
      BrianP
      Participant

      Pat,

      Sorry for the latest bump in the road.  Has your son looked for PD-1 trials.  Seems like I've seen one or two lately that do allow for prior IPI treatments.  You may try to post on MIF and see if Catherine Poole knows of any.  She's a great resource for the latest and greatest on Nivo trials.  Good luck to you and your son.

      Brian

      • January 7, 2014 at 3:06 am
      BrianP
      Participant

      Pat,

      Sorry for the latest bump in the road.  Has your son looked for PD-1 trials.  Seems like I've seen one or two lately that do allow for prior IPI treatments.  You may try to post on MIF and see if Catherine Poole knows of any.  She's a great resource for the latest and greatest on Nivo trials.  Good luck to you and your son.

      Brian

      • January 7, 2014 at 3:33 am
      POW
      Participant

      There are very few anti-PD1 trials open now. However, a new treatment called anti-PD-L1 is expanding trials and it may be even better than anti-PD1. Catherine Poole at the Melanoma International Foundation just posted this today. 

      Here is a new PDL trial opening very soon: http://clinicaltrials.gov/ct2/show/NCT0 … 736&rank=1



      Locations are listed and there may be more. It is for both BRAF positive and BRAF negative.

      You can't have prior BRAF drugs. But didn't see any other exclusions for prior therapy.
      Catherine M. Poole, President/Founder
      • January 7, 2014 at 3:33 am
      POW
      Participant

      There are very few anti-PD1 trials open now. However, a new treatment called anti-PD-L1 is expanding trials and it may be even better than anti-PD1. Catherine Poole at the Melanoma International Foundation just posted this today. 

      Here is a new PDL trial opening very soon: http://clinicaltrials.gov/ct2/show/NCT0 … 736&rank=1



      Locations are listed and there may be more. It is for both BRAF positive and BRAF negative.

      You can't have prior BRAF drugs. But didn't see any other exclusions for prior therapy.
      Catherine M. Poole, President/Founder
      • January 7, 2014 at 3:33 am
      POW
      Participant

      There are very few anti-PD1 trials open now. However, a new treatment called anti-PD-L1 is expanding trials and it may be even better than anti-PD1. Catherine Poole at the Melanoma International Foundation just posted this today. 

      Here is a new PDL trial opening very soon: http://clinicaltrials.gov/ct2/show/NCT0 … 736&rank=1



      Locations are listed and there may be more. It is for both BRAF positive and BRAF negative.

      You can't have prior BRAF drugs. But didn't see any other exclusions for prior therapy.
      Catherine M. Poole, President/Founder
Viewing 5 reply threads

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