Excluded father from R05185426 treatment in the Netherlands.. help
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Excluded father from R05185426 treatment in the Netherlands.. help

› Forums › General Melanoma Community › Excluded father from R05185426 treatment in the Netherlands.. help

  • Post
    • June 7, 2012 at 4:56 pm
    youri hasper
    Participant

    Hello everyone,

    My name is Youri and I live in the Netherlands.
    My father has been sick for a long time and after succesfull radiation therapies, my fathers melanoma's were stable for over a year. In the pas couple of months the melanoma's started growing again. Radiation and chemo didn't work this time. 

    Hello everyone,

    My name is Youri and I live in the Netherlands.
    My father has been sick for a long time and after succesfull radiation therapies, my fathers melanoma's were stable for over a year. In the pas couple of months the melanoma's started growing again. Radiation and chemo didn't work this time. 

    We heard about a new treatment, called R05185426, which possibly would lead to stabilisation, or even shrinking of the melanoma's. In the Netherlands this treatment is still in the experimental stage. An entrance requirement is that the melanoma's above the shoulders are stable. Unfortunately my fathers aren't. Yesterday the doctor told us that my father is excluded from the new treatment. 

    My question is, whether in other countries than the Netherland, the treatment can be performed or the new chemo can be optained on the free market. 
    We are almost out of hope so if you know anything, please reply, and help us.

    With kind regards,

    Youri Hasper and family

     

Viewing 8 reply threads
  • Replies
      • June 7, 2012 at 9:46 pm
      Richard_K
      Participant
      RO5185426 is also vemurafenib, or Zelboraf. EU approval was granted on 20 Feb 2012. Hope this helps
      Dick
      • June 7, 2012 at 9:46 pm
      Richard_K
      Participant
      RO5185426 is also vemurafenib, or Zelboraf. EU approval was granted on 20 Feb 2012. Hope this helps
      Dick
      • June 7, 2012 at 9:46 pm
      Richard_K
      Participant
      RO5185426 is also vemurafenib, or Zelboraf. EU approval was granted on 20 Feb 2012. Hope this helps
      Dick
      • June 7, 2012 at 11:02 pm
      washoegal
      Participant

      You might find other alternatives that would be suitable for your father if you check the Melanoma Interational Foundation website.  One of their websight coordinators is from the "other side of the pond".

      Good Luck,

      Mary

      Stage 3

      • June 7, 2012 at 11:02 pm
      washoegal
      Participant

      You might find other alternatives that would be suitable for your father if you check the Melanoma Interational Foundation website.  One of their websight coordinators is from the "other side of the pond".

      Good Luck,

      Mary

      Stage 3

      • June 7, 2012 at 11:02 pm
      washoegal
      Participant

      You might find other alternatives that would be suitable for your father if you check the Melanoma Interational Foundation website.  One of their websight coordinators is from the "other side of the pond".

      Good Luck,

      Mary

      Stage 3

      • June 8, 2012 at 1:37 pm
      LynnLuc
      Participant

      you should also go to http://www.cancer.gov to check out clinical trials – check out the criteria to give you a good idea on what your father may be able to use.

      • June 8, 2012 at 1:37 pm
      LynnLuc
      Participant

      you should also go to http://www.cancer.gov to check out clinical trials – check out the criteria to give you a good idea on what your father may be able to use.

        • June 11, 2012 at 10:15 am
        youri hasper
        Participant

        Thank you all for the reactions they were usefull. Now i'm trying to find clinical trails in other countries in Europe where stability above the neck isn't a requirement for the trails. 

        I have to admit that my mastery of english makes it hard for me to understand the scientific papers. It takes a lot of time to analyse the different options. So if anyone nows a place in Europe where the stability, above the neck, isn't an issue, please let me know.

        A short update about my father:
        He is still in the hospital and finaly on morphine drugs. Also he had a special bed which makes his legs and hip hurt less.
        Yesterday we have renoveded the ground floor in our home to make it possible for him to live downstairs. He lookt much better and the pain is, thanks to the drugs, much less. He finally has occasionally a smile on his face.

        Again, if someone has experience with R05185326 (Vemurafenib, plx4032) treatment in Europe, while having unstable melanoma's above the neck, please tell me where this was and help me contact the right people.

        With kind regards,

        Youri

        • June 11, 2012 at 10:15 am
        youri hasper
        Participant

        Thank you all for the reactions they were usefull. Now i'm trying to find clinical trails in other countries in Europe where stability above the neck isn't a requirement for the trails. 

        I have to admit that my mastery of english makes it hard for me to understand the scientific papers. It takes a lot of time to analyse the different options. So if anyone nows a place in Europe where the stability, above the neck, isn't an issue, please let me know.

        A short update about my father:
        He is still in the hospital and finaly on morphine drugs. Also he had a special bed which makes his legs and hip hurt less.
        Yesterday we have renoveded the ground floor in our home to make it possible for him to live downstairs. He lookt much better and the pain is, thanks to the drugs, much less. He finally has occasionally a smile on his face.

        Again, if someone has experience with R05185326 (Vemurafenib, plx4032) treatment in Europe, while having unstable melanoma's above the neck, please tell me where this was and help me contact the right people.

        With kind regards,

        Youri

        • June 11, 2012 at 10:15 am
        youri hasper
        Participant

        Thank you all for the reactions they were usefull. Now i'm trying to find clinical trails in other countries in Europe where stability above the neck isn't a requirement for the trails. 

        I have to admit that my mastery of english makes it hard for me to understand the scientific papers. It takes a lot of time to analyse the different options. So if anyone nows a place in Europe where the stability, above the neck, isn't an issue, please let me know.

        A short update about my father:
        He is still in the hospital and finaly on morphine drugs. Also he had a special bed which makes his legs and hip hurt less.
        Yesterday we have renoveded the ground floor in our home to make it possible for him to live downstairs. He lookt much better and the pain is, thanks to the drugs, much less. He finally has occasionally a smile on his face.

        Again, if someone has experience with R05185326 (Vemurafenib, plx4032) treatment in Europe, while having unstable melanoma's above the neck, please tell me where this was and help me contact the right people.

        With kind regards,

        Youri

        • June 11, 2012 at 10:15 am
        youri hasper
        Participant

        Thank you all for the reactions they were usefull. Now i'm trying to find clinical trails in other countries in Europe where stability above the neck isn't a requirement for the trails. 

        I have to admit that my mastery of english makes it hard for me to understand the scientific papers. It takes a lot of time to analyse the different options. So if anyone nows a place in Europe where the stability, above the neck, isn't an issue, please let me know.

        A short update about my father:
        He is still in the hospital and finaly on morphine drugs. Also he had a special bed which makes his legs and hip hurt less.
        Yesterday we have renoveded the ground floor in our home to make it possible for him to live downstairs. He lookt much better and the pain is, thanks to the drugs, much less. He finally has occasionally a smile on his face.

        Again, if someone has experience with R05185326 (Vemurafenib, plx4032) treatment in Europe, while having unstable melanoma's above the neck, please tell me where this was and help me contact the right people.

        With kind regards,

        Youri

        • June 11, 2012 at 10:15 am
        youri hasper
        Participant

        Thank you all for the reactions they were usefull. Now i'm trying to find clinical trails in other countries in Europe where stability above the neck isn't a requirement for the trails. 

        I have to admit that my mastery of english makes it hard for me to understand the scientific papers. It takes a lot of time to analyse the different options. So if anyone nows a place in Europe where the stability, above the neck, isn't an issue, please let me know.

        A short update about my father:
        He is still in the hospital and finaly on morphine drugs. Also he had a special bed which makes his legs and hip hurt less.
        Yesterday we have renoveded the ground floor in our home to make it possible for him to live downstairs. He lookt much better and the pain is, thanks to the drugs, much less. He finally has occasionally a smile on his face.

        Again, if someone has experience with R05185326 (Vemurafenib, plx4032) treatment in Europe, while having unstable melanoma's above the neck, please tell me where this was and help me contact the right people.

        With kind regards,

        Youri

        • June 11, 2012 at 10:15 am
        youri hasper
        Participant

        Thank you all for the reactions they were usefull. Now i'm trying to find clinical trails in other countries in Europe where stability above the neck isn't a requirement for the trails. 

        I have to admit that my mastery of english makes it hard for me to understand the scientific papers. It takes a lot of time to analyse the different options. So if anyone nows a place in Europe where the stability, above the neck, isn't an issue, please let me know.

        A short update about my father:
        He is still in the hospital and finaly on morphine drugs. Also he had a special bed which makes his legs and hip hurt less.
        Yesterday we have renoveded the ground floor in our home to make it possible for him to live downstairs. He lookt much better and the pain is, thanks to the drugs, much less. He finally has occasionally a smile on his face.

        Again, if someone has experience with R05185326 (Vemurafenib, plx4032) treatment in Europe, while having unstable melanoma's above the neck, please tell me where this was and help me contact the right people.

        With kind regards,

        Youri

      • June 8, 2012 at 1:37 pm
      LynnLuc
      Participant

      you should also go to http://www.cancer.gov to check out clinical trials – check out the criteria to give you a good idea on what your father may be able to use.

Viewing 8 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.