ippi and radiation
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ippi and radiation

› Forums › General Melanoma Community › ippi and radiation

  • Post
    • April 4, 2012 at 12:32 am
    bikerwife
    Participant
    We finished ippi march 26. Went in for a follow up from gamma knife. They treated 5 small lesions on brain they said scan in 6 weeks and it should show shrinkeage. They also wanted to look at the growths one under arn is size of a quarter. Thought that was it went home. Got a call today and they have consulted with our dr and they want to do radiation with gamma under arm. Said a new study shows radiation boost the tumors and makes them regress faster. I’m so confused at first they said 10 and know only 5. I’m so confused but lynn says we will just pray about it.

    We finished ippi march 26. Went in for a follow up from gamma knife. They treated 5 small lesions on brain they said scan in 6 weeks and it should show shrinkeage. They also wanted to look at the growths one under arn is size of a quarter. Thought that was it went home. Got a call today and they have consulted with our dr and they want to do radiation with gamma under arm. Said a new study shows radiation boost the tumors and makes them regress faster. I’m so confused at first they said 10 and know only 5. I’m so confused but lynn says we will just pray about it. Whatever God brings us to he will take us through. God bless each of you and thanks for listening.

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  • Replies
      • April 4, 2012 at 12:43 am
      aldakota22
      Participant

      Such a rough ride for both of you.We are all here to listen to you and offer prayers and what little help and support.we can Al

      • April 4, 2012 at 12:43 am
      aldakota22
      Participant

      Such a rough ride for both of you.We are all here to listen to you and offer prayers and what little help and support.we can Al

      • April 4, 2012 at 12:43 am
      aldakota22
      Participant

      Such a rough ride for both of you.We are all here to listen to you and offer prayers and what little help and support.we can Al

      • April 4, 2012 at 10:33 am
      MeNDave
      Participant

      His doctor is right – radiation can bump up the effects of IPI, even if he hasn't seen a response yet.

      I hope it does the trick, and gets those tumors shrinking.

      All the best,

      Maria

      • April 4, 2012 at 10:33 am
      MeNDave
      Participant

      His doctor is right – radiation can bump up the effects of IPI, even if he hasn't seen a response yet.

      I hope it does the trick, and gets those tumors shrinking.

      All the best,

      Maria

      • April 4, 2012 at 10:33 am
      MeNDave
      Participant

      His doctor is right – radiation can bump up the effects of IPI, even if he hasn't seen a response yet.

      I hope it does the trick, and gets those tumors shrinking.

      All the best,

      Maria

      • April 4, 2012 at 6:05 pm
      kylez
      Participant

      An oncologist from Sloan Kettering recently published a 1-patient observation of something called the abscopal effect, wherein radiation on one tumor, combined with concurrent IPI, appeared to boost the effect of IPI on other tumors that weren't radiated. They believe with this particular patient, that the radiation cut loose a 'bits and pieces', i.e. antigens, from the one tumor that the helped the IPI-boosted immune respond more strongly in the patient's unradidated tumors as well.

      It sounds like your docs are making this offering (combining radiation with IPI) based on this concept — theories — unconfirmed as of yet by wide clinical trials but supported as highly plausible. There's at least one clinical trial testing this concept, I believe it's http://clinicaltrials.gov/ct2/show/NCT01449279. It sounds like a good opportunity to me.

      Why they're not offering to Gamma Knife the small brain mets is another question I would ask them, though.

      Good luck, Kyle

      • April 4, 2012 at 6:05 pm
      kylez
      Participant

      An oncologist from Sloan Kettering recently published a 1-patient observation of something called the abscopal effect, wherein radiation on one tumor, combined with concurrent IPI, appeared to boost the effect of IPI on other tumors that weren't radiated. They believe with this particular patient, that the radiation cut loose a 'bits and pieces', i.e. antigens, from the one tumor that the helped the IPI-boosted immune respond more strongly in the patient's unradidated tumors as well.

      It sounds like your docs are making this offering (combining radiation with IPI) based on this concept — theories — unconfirmed as of yet by wide clinical trials but supported as highly plausible. There's at least one clinical trial testing this concept, I believe it's http://clinicaltrials.gov/ct2/show/NCT01449279. It sounds like a good opportunity to me.

      Why they're not offering to Gamma Knife the small brain mets is another question I would ask them, though.

      Good luck, Kyle

        • April 5, 2012 at 1:52 am
        bikerwife
        Participant
        Thanks everyone for the thoughtful words and Kyle we had gamma knife on brain mets feb 20. Its working cause we have faith in God and he’s got this.
        • April 5, 2012 at 1:52 am
        bikerwife
        Participant
        Thanks everyone for the thoughtful words and Kyle we had gamma knife on brain mets feb 20. Its working cause we have faith in God and he’s got this.
        • April 5, 2012 at 1:52 am
        bikerwife
        Participant
        Thanks everyone for the thoughtful words and Kyle we had gamma knife on brain mets feb 20. Its working cause we have faith in God and he’s got this.
      • April 4, 2012 at 6:05 pm
      kylez
      Participant

      An oncologist from Sloan Kettering recently published a 1-patient observation of something called the abscopal effect, wherein radiation on one tumor, combined with concurrent IPI, appeared to boost the effect of IPI on other tumors that weren't radiated. They believe with this particular patient, that the radiation cut loose a 'bits and pieces', i.e. antigens, from the one tumor that the helped the IPI-boosted immune respond more strongly in the patient's unradidated tumors as well.

      It sounds like your docs are making this offering (combining radiation with IPI) based on this concept — theories — unconfirmed as of yet by wide clinical trials but supported as highly plausible. There's at least one clinical trial testing this concept, I believe it's http://clinicaltrials.gov/ct2/show/NCT01449279. It sounds like a good opportunity to me.

      Why they're not offering to Gamma Knife the small brain mets is another question I would ask them, though.

      Good luck, Kyle

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