› Forums › General Melanoma Community › Looking for Weber PD1 (1106) patients
- This topic has 14 replies, 4 voices, and was last updated 13 years, 3 months ago by Bubbles.
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- September 24, 2011 at 9:29 pm
I am considering doing a trial with Weber at Moffitt (PD1 + antibody – 1106). I only know of 1 person on it right now. If anyone else is on it and willing to share please write back. Thanks.
I am considering doing a trial with Weber at Moffitt (PD1 + antibody – 1106). I only know of 1 person on it right now. If anyone else is on it and willing to share please write back. Thanks.
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- September 24, 2011 at 10:19 pm
I'm not on the trial, but can you post a link to the trial?
Thanks,
Robert
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- September 25, 2011 at 12:00 am
Just had my scans and 2nd booster of Anti PD 1- NED now since March 26, 2010.o/o/o/
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- September 25, 2011 at 12:06 am
although I had to wait a week- due to the Optiscan 320 dye they use with the CT- I went into shock and it was pretty bad- I knew it was when I couldn't breathe and they stabbed me in my chest with adrenaline…seems I cannot do anymore CT's with dye 😮 which is actually OK with me!I can't do any iodated contrast medium dye anymore actually.
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- September 25, 2011 at 12:06 am
although I had to wait a week- due to the Optiscan 320 dye they use with the CT- I went into shock and it was pretty bad- I knew it was when I couldn't breathe and they stabbed me in my chest with adrenaline…seems I cannot do anymore CT's with dye 😮 which is actually OK with me!I can't do any iodated contrast medium dye anymore actually.
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- September 25, 2011 at 12:00 am
Just had my scans and 2nd booster of Anti PD 1- NED now since March 26, 2010.o/o/o/
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- September 25, 2011 at 2:14 pm
I am on the study you refer to, first cohort, resected. There is a sister study with non resected patients. This is a Phase 1 clinical trial so the goal is to find the dosage that is most effective with least side effects. Comparison with other drugs will come later. Therefore, you are taking drugs that have been used with few human subjects, but you are certain to get the med. There are to be three cohorts with three doses of anti-PD1 (1, 3, and 10mg/kg) infused every 2 weeks for 6 months, then every 3 months for a total of 2 years. Peptide vaccines (6 of them) are injected at each of your every 2 week visits. Scans are every 3 months with meds to follow if you remain NED. As far as l know they are enrolling patients into the 3mg/kg cohort at this time. The 10mg/kg group will only start depending on how the prior group tolerates the med. For more about me you can check the bio here. For my history and stories of the 9 months on the trial check: chaoticallypreciselifeloveandmelanoma.blogspot.com -
- September 25, 2011 at 2:14 pm
I am on the study you refer to, first cohort, resected. There is a sister study with non resected patients. This is a Phase 1 clinical trial so the goal is to find the dosage that is most effective with least side effects. Comparison with other drugs will come later. Therefore, you are taking drugs that have been used with few human subjects, but you are certain to get the med. There are to be three cohorts with three doses of anti-PD1 (1, 3, and 10mg/kg) infused every 2 weeks for 6 months, then every 3 months for a total of 2 years. Peptide vaccines (6 of them) are injected at each of your every 2 week visits. Scans are every 3 months with meds to follow if you remain NED. As far as l know they are enrolling patients into the 3mg/kg cohort at this time. The 10mg/kg group will only start depending on how the prior group tolerates the med. For more about me you can check the bio here. For my history and stories of the 9 months on the trial check: chaoticallypreciselifeloveandmelanoma.blogspot.com -
- September 26, 2011 at 2:05 am
Yes, the HLA typing is an important point for access to this study. That is due to the vaccine component, not the anti-PD1. I am sorry for those who were not allowed in because of that. It is a tough trial. For me two days travel with each treatment has added to its challenges. However, l have worked full time throughout as an NP, missing only 2 days of work while on the study. Hang in there. Wishing each of you the very best. -
- September 26, 2011 at 2:05 am
Yes, the HLA typing is an important point for access to this study. That is due to the vaccine component, not the anti-PD1. I am sorry for those who were not allowed in because of that. It is a tough trial. For me two days travel with each treatment has added to its challenges. However, l have worked full time throughout as an NP, missing only 2 days of work while on the study. Hang in there. Wishing each of you the very best.
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