FYI an exciting trial It uses Anti PD 1 and ipi!
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FYI an exciting trial It uses Anti PD 1 and ipi!

› Forums › General Melanoma Community › FYI an exciting trial It uses Anti PD 1 and ipi!

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      • July 2, 2011 at 1:49 pm
      LynnLuc
      Participant

      It's NOT Anti PD 1 LOL I need my glasses…still exciting tho

      • July 2, 2011 at 1:49 pm
      LynnLuc
      Participant

      It's NOT Anti PD 1 LOL I need my glasses…still exciting tho

        • July 2, 2011 at 1:55 pm
        nicoli
        Participant

        It's okay. Needing glasses just means we're getting OLD. And we who are fighting the beast LOVE TO GET OLD 🙂 I hope you live to be 100 !!

        Old and ALIVE, Nicki, Stage 3b

        • July 2, 2011 at 1:55 pm
        nicoli
        Participant

        It's okay. Needing glasses just means we're getting OLD. And we who are fighting the beast LOVE TO GET OLD 🙂 I hope you live to be 100 !!

        Old and ALIVE, Nicki, Stage 3b

        • July 2, 2011 at 6:45 pm
        LynnLuc
        Participant

        You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

        • July 2, 2011 at 6:45 pm
        LynnLuc
        Participant

        You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

        • July 2, 2011 at 6:46 pm
        LynnLuc
        Participant

        You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

        • July 2, 2011 at 6:46 pm
        LynnLuc
        Participant

        You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

        • July 2, 2011 at 6:47 pm
        LynnLuc
        Participant

        It really is the first time in my life I can say I am happy to be getting old!! I don't like wearing glasses though!!

        • July 2, 2011 at 6:47 pm
        LynnLuc
        Participant

        It really is the first time in my life I can say I am happy to be getting old!! I don't like wearing glasses though!!

        • July 2, 2011 at 1:58 pm
        MariaH
        Participant

        Thanks for posting Lynn!  We are going to try and get Dave into one of these clinical trials – and I want him seen at UPMC also – they have a trial with IPI and GM-GSF. He sees the thoracic surgeon on Wednesday for post op check up – we'll have a boat load of questions for him then.

        • July 2, 2011 at 1:58 pm
        MariaH
        Participant

        Thanks for posting Lynn!  We are going to try and get Dave into one of these clinical trials – and I want him seen at UPMC also – they have a trial with IPI and GM-GSF. He sees the thoracic surgeon on Wednesday for post op check up – we'll have a boat load of questions for him then.

        • July 2, 2011 at 4:42 pm
        Cooper
        Participant

        I think this is a trial for BRAF and IPI  NOT anti pd1 and IPI.sad

        • July 2, 2011 at 4:42 pm
        Cooper
        Participant

        I think this is a trial for BRAF and IPI  NOT anti pd1 and IPI.sad

        • July 2, 2011 at 6:44 pm
        LynnLuc
        Participant

        yep, you're right…I posted right afterwards…I put my glasses on!

        • July 2, 2011 at 6:44 pm
        LynnLuc
        Participant

        yep, you're right…I posted right afterwards…I put my glasses on!

      • July 3, 2011 at 4:47 am
      kylez
      Participant

      Hi Lynn,

      Here's a combo trial of MDX-1106 and IPI:

      http://clinicaltrials.gov/ct2/show/NCT01024231

      I started IPI (infusion #1) last week.

      – Kyle

      • July 3, 2011 at 4:47 am
      kylez
      Participant

      Hi Lynn,

      Here's a combo trial of MDX-1106 and IPI:

      http://clinicaltrials.gov/ct2/show/NCT01024231

      I started IPI (infusion #1) last week.

      – Kyle

        • July 3, 2011 at 4:52 am
        LynnLuc
        Participant

        I think this is the best trial to date!

        • July 3, 2011 at 4:52 am
        LynnLuc
        Participant

        I think this is the best trial to date!

        • July 4, 2011 at 1:34 pm
        nickmac56
        Participant

        does anyone know what this exclusion for this trial means?  On the surface that would say you need to be NED or stable – but hard to believe it would be that restrictive.

         

        Prior malignancy active within the previous 2 years

        • July 4, 2011 at 4:06 pm
        kylez
        Participant

        with an inclusion criteria of "Measurable unresectable Stage III or IV MEL", I believe an exclusion criteria of "Prior malignancy active within the previous 2 years" usually means if there was another cancer other than melanoma.

        For example, a more explicitly worded exclusion criteria I've seen is "Prior malignancy within the preceding five years, with the exception of non-melanoma skin cancers."

        • July 4, 2011 at 4:06 pm
        kylez
        Participant

        with an inclusion criteria of "Measurable unresectable Stage III or IV MEL", I believe an exclusion criteria of "Prior malignancy active within the previous 2 years" usually means if there was another cancer other than melanoma.

        For example, a more explicitly worded exclusion criteria I've seen is "Prior malignancy within the preceding five years, with the exception of non-melanoma skin cancers."

        • July 4, 2011 at 1:34 pm
        nickmac56
        Participant

        does anyone know what this exclusion for this trial means?  On the surface that would say you need to be NED or stable – but hard to believe it would be that restrictive.

         

        Prior malignancy active within the previous 2 years

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