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Complete Response

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  • Post
    • May 31, 2011 at 11:26 pm
    Bill G
    Participant

    Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T Cell Transfer Immunotherapy

    Clin Cancer Res.

    Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T Cell Transfer Immunotherapy

    Clin Cancer Res. 2011 Apr 15;[Epub Ahead of Print], SA Rosenberg, JC Yang, RM Sherry, US Kammula, MS Hughes, GQ Phan, DE Citrin, NP Restifo, PF Robbins, JR Wunderlich, KE Morton, CM Laurencot, SM Steinberg, DE White, ME Dudley 

    Currently available and experimental therapies for metastatic melanoma produce very few durable complete responses and, thus, a low chance of cure. Rosenberg et al from the National Cancer Institute report results of a new approach for these patients: the adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) selected for antitumor activity and expanded in vitro. The study involved 93 patients with metastatic melanoma who were heavily pretreated with standard and experimental regimens…. 

    http://www.oncologystat.com/journals/journal_scans/Durable_Complete_Responses_in_Heavily_Pretreated_Patients_with_Metastatic_Melanoma_Using_T_Cell_Transfer_Immunotherapy.html 

     

Viewing 5 reply threads
  • Replies
      • May 31, 2011 at 11:40 pm
      washoegal
      Participant

      This is such wonderful news since there is so little out there which actually promises a durable response.  However, and of course, don't we always have a "however" in our world, this treatment is extremely time consuming and labor intensive.  I have to wonder what the cost and what the reaction of the insurance companies will be.  Just thinking out loud (or in type).

      Mary

      Stage 3

      • May 31, 2011 at 11:40 pm
      washoegal
      Participant

      This is such wonderful news since there is so little out there which actually promises a durable response.  However, and of course, don't we always have a "however" in our world, this treatment is extremely time consuming and labor intensive.  I have to wonder what the cost and what the reaction of the insurance companies will be.  Just thinking out loud (or in type).

      Mary

      Stage 3

      • June 1, 2011 at 1:05 am
      mygirlmaddy
      Participant

      This is the treatment recommended as the next step for my husband.  We are still in the infant stages of the planning but I will gladly post our experience and progress.  Thank you for taking the time to post the information.

      • June 1, 2011 at 1:05 am
      mygirlmaddy
      Participant

      This is the treatment recommended as the next step for my husband.  We are still in the infant stages of the planning but I will gladly post our experience and progress.  Thank you for taking the time to post the information.

      • June 1, 2011 at 1:25 am
      nicoli
      Participant

      Thanks so much for posting. I was just telling my husband, "seems like just about everything I know about melanoma, I learned from this site."

      Thanks again,

      Nicki, Stage 3b

      • June 1, 2011 at 1:25 am
      nicoli
      Participant

      Thanks so much for posting. I was just telling my husband, "seems like just about everything I know about melanoma, I learned from this site."

      Thanks again,

      Nicki, Stage 3b

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