Question?
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Question?

› Forums › General Melanoma Community › Question?

  • Post
    • May 17, 2018 at 6:09 pm
    Coragirl
    Participant

    My husband had his first infusion of Opdivo a week ago today. He is feeling good and hasn't really had any side effects except a little fatigue the day after the infusion. Do side effects increase with each infusion? If he isn t experiencing side effects does that mean it's not working? I hope I'm not asking dumb questions. Thanks any feedback is appreciated.

Viewing 4 reply threads
  • Replies
      • May 17, 2018 at 6:45 pm
      cancersnewnormal
      Participant

      Side effects don't necessarily correspond with treatment efficacy. I had very few side effects with Keytruda until 18-20 months into infusions, and it worked quite well in eliminating my lesions, as well as stopping anything new from cropping up. Best wishes for good results and continued lack of side effects! 🙂

        • May 17, 2018 at 11:20 pm
        Coragirl
        Participant

        Thank you. 

      • May 17, 2018 at 6:47 pm
      Hukill
      Participant

      I would say it may still be early to notice any significant side effects. I started on the combo with Yervoy being the one causing most of the quick side effects. The rash came towards the end of the second week and 24 months later I still have it. I have noticed after the double dose it flares up for about a week but has really never itched until the double dose and then only in new spots on the back of both hands. My fatiuge has been horrible along with insomnia. I often fall asleep at my desk at work. Some days I go home and go straight to bed. Be patient.

      • May 17, 2018 at 6:51 pm
      Hukill
      Participant

      I also want to say I have had 6 side effects that all came about while on the combo, since I have been on just opdivo I still have 5 of the side effects and have not had any new ones.

        • May 17, 2018 at 11:21 pm
        Coragirl
        Participant

        Thanks for answering my questions

      • May 18, 2018 at 3:15 pm
      ed williams
      Participant

      Hi Amie, here is a link to a detailed report on side effects of check point inhibitors developed by SITC, which is an organization for Immunotherapy oncologist and researchers. The report is broken down into sections with stats and how to treat based on how sever the side effect. I hope you find it helpful, also remember that most of us on Nivo have low grade versions of the side effects and if caught early and treated they are usually easy to reverse. Best Wishes!!!Ed https://jitc.biomedcentral.com/articles/10.1186/s40425-017-0300-z

        • May 18, 2018 at 4:48 pm
        Coragirl
        Participant

        Thank you Ed, you are so very helpful to do many of us! Hope you are well.

        • May 18, 2018 at 5:40 pm
        ed williams
        Participant

        I am doing good thank you, just finished treatment this morning and now I am heading for a nap!!!

      • May 19, 2018 at 4:52 pm
      jennunicorn
      Participant

      I had very mild side effects for the most part. I am grateful to have no lasting effects from treatment and it worked! So, hopefully your husband continues to have very few side effects and gets a great response as well. 

        • May 20, 2018 at 12:54 am
        Coragirl
        Participant

        Thank you! 

Viewing 4 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

Popular Topics