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Pathology report help

This topic has 3 replies, 3 voices, and was last updated 8 years ago by wildwilly69.

Post

- February 22, 2018 at 9:21 pm
- Quote
wildwilly69
Participant

Hi,

I received a pathology report below and not sure what it means. I have been scheduled to have a wider section removed based on this report. I need help understanding the report.

FINAL
MICROSCOPIC
DIAGNOSIS: A. Right pretibia, Shave Biopsy:"" SEVERELY
ATYPICAL
INTRAEPIDERMAL
MELANOCYTIC
PROLIFERATION
W ITH DENSE
HOST RESPONSE;
EXTENDING TO
ONE PERIPHERAL
MARGIN."" "" Comment:
Although the
findings are not
sufficient to
render a
definitive
diagnosis of
melanoma in
situ, the lesion is
significantly
atypical. Initial
and multiple
deeper sections
were examined. A
MART-1
immunostain
(with appropriate
controls)
highlights
melanocyte
distribution and
supports the
above diagnosis. Sections show a
proliferation of
atypical
melanocytes at
the
dermoepidermal
junction, with
areas of
confluence.

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Replies

- - February 23, 2018 at 5:01 pm
  - Quote
  ed williams
  Participant
  
  Hi Anon, didn't want to leave you hanging any longer, I am sure one of the early stage experts will chime in but as I read it, no big deal, you caught things early enough. Pretty sure you are just looking at getting good margins and then follow the instructions that Dermatologist gives you. If you go back and look at older post of insitu or Atypical path reports, look for the name Janner, any post where she gives advice to similiar early path reports are gold as far as good advice. Take Care!!!Ed
- - February 23, 2018 at 6:14 pm
  - Quote
  Janner
  Participant
  
  The diagnosis is NOT melanoma. It is a severely atypical lesion. However, most doctors recommend having additional margins removed. The margins recommended are actually the same margins (5 mm) you would have removed if you had a very early melanoma. Early melanomas are called "in situ". So this isn't melanoma and may never had become melanoma, but it's close enough to be cautious and have extra skin removed – just in case. Continue to watch your other moles for change!
  - February 23, 2018 at 7:29 pm
    
    Quote
    wildwilly69
    Participant
    
    Thank you for the explanation of the report. I'm scheduled to have more removed and will watch other moles for changes. Thank you again.

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