Good news on NYE – Ipi response!
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Good news on NYE – Ipi response!

› Forums › General Melanoma Community › Good news on NYE – Ipi response!

  • Post
    • December 31, 2015 at 1:59 pm
    bonusfries
    Participant

    I had progressed while on BRAF + MEK (2cm adrenal mets), and since the new growth was limited and small, we did the 4 infusion cycle of ipi starting in the beginning of August.

    An interview I had read from Celeste's blog said most people who progress on BRAF don't respond to ipi, so I did not have high hopes for this treatment.

    My last infusion was on October 9th. While my side effects were rather impactful, my blood work and overall health were good throughout so we waited as long as possible for follow-up scans.

    My follow-up CT shows no traces of the mets, nor did it find anything new! The side effects were well worth that radiology report.

    Clean scans for all in 2016!

    Jeff

Viewing 11 reply threads
  • Replies
      • December 31, 2015 at 2:22 pm
      mjanssentx
      Participant

      Jeff – that is great news….have a great new years…Michel

      • December 31, 2015 at 2:22 pm
      mjanssentx
      Participant

      Jeff – that is great news….have a great new years…Michel

      • December 31, 2015 at 2:22 pm
      mjanssentx
      Participant

      Jeff – that is great news….have a great new years…Michel

      • December 31, 2015 at 4:51 pm
      Bubbles
      Participant

      Oh, Jeff that is wonderful news indeed! (Not the side effects of course, but the great results!)

      I am a little unsure about what gave you your concerns about a response to ipi after failing BRAFi. Most data report response to ipi in that circumstance to be about the same as when taking ipi for the first time:  

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/11/data-on-brafi-combos-and-effects-of-ipi.html

      The contradiction in data regarding response rates usually revolves around whether to take anti-PD1 or ipi first in order to achieve the best response.  But either way…..your news is excellent! 

      I wish you my best and a wonderful 2016!  Celeste

      • December 31, 2015 at 4:51 pm
      Bubbles
      Participant

      Oh, Jeff that is wonderful news indeed! (Not the side effects of course, but the great results!)

      I am a little unsure about what gave you your concerns about a response to ipi after failing BRAFi. Most data report response to ipi in that circumstance to be about the same as when taking ipi for the first time:  

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/11/data-on-brafi-combos-and-effects-of-ipi.html

      The contradiction in data regarding response rates usually revolves around whether to take anti-PD1 or ipi first in order to achieve the best response.  But either way…..your news is excellent! 

      I wish you my best and a wonderful 2016!  Celeste

      • December 31, 2015 at 4:51 pm
      Bubbles
      Participant

      Oh, Jeff that is wonderful news indeed! (Not the side effects of course, but the great results!)

      I am a little unsure about what gave you your concerns about a response to ipi after failing BRAFi. Most data report response to ipi in that circumstance to be about the same as when taking ipi for the first time:  

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/11/data-on-brafi-combos-and-effects-of-ipi.html

      The contradiction in data regarding response rates usually revolves around whether to take anti-PD1 or ipi first in order to achieve the best response.  But either way…..your news is excellent! 

      I wish you my best and a wonderful 2016!  Celeste

      • December 31, 2015 at 9:33 pm
      Jubes
      Participant

      Brilliant!! Thanks for posting. Gives us all hope! 

      • December 31, 2015 at 9:33 pm
      Jubes
      Participant

      Brilliant!! Thanks for posting. Gives us all hope! 

      • December 31, 2015 at 9:33 pm
      Jubes
      Participant

      Brilliant!! Thanks for posting. Gives us all hope! 

      • December 31, 2015 at 10:29 pm
      Eileensulliv
      Participant

      Fantastic news, Jeff! What a great way to start 2016!

      • December 31, 2015 at 10:29 pm
      Eileensulliv
      Participant

      Fantastic news, Jeff! What a great way to start 2016!

      • December 31, 2015 at 10:29 pm
      Eileensulliv
      Participant

      Fantastic news, Jeff! What a great way to start 2016!

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