› Forums › General Melanoma Community › YERVOY VS. ZELBORAF need any info
- This topic has 4 replies, 2 voices, and was last updated 13 years, 4 months ago by sss.
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- September 10, 2011 at 11:48 pm
I expect to start a treatment this week for mel. recurring. Has anyone had experience w. zelboraf. I know its very new on market but has anyone started this drug. Any effects good or bad. Please help.
I expect to start a treatment this week for mel. recurring. Has anyone had experience w. zelboraf. I know its very new on market but has anyone started this drug. Any effects good or bad. Please help.
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- September 11, 2011 at 12:40 am
Do a search for Zelboraf or BRAF or vemurafenib. You wil find that many people here have been in the Roche/Plexxikon Studies.
http://www.roche.com/media/media_releases/med-cor-2011-08-17.htm
If this treatment starts to work, it does so quickly. How long it will work varies by the person. For some a short time, for others it has worked for several years and is still working. Good luck i getting info from the search. I do not have the V600^ mutation so no personal experience with it.
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- September 11, 2011 at 12:40 am
Do a search for Zelboraf or BRAF or vemurafenib. You wil find that many people here have been in the Roche/Plexxikon Studies.
http://www.roche.com/media/media_releases/med-cor-2011-08-17.htm
If this treatment starts to work, it does so quickly. How long it will work varies by the person. For some a short time, for others it has worked for several years and is still working. Good luck i getting info from the search. I do not have the V600^ mutation so no personal experience with it.
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- September 12, 2011 at 4:27 pm
I started Zelboraf 8/2/11 as part of clinical trial. 2 weeks into initial month, drug approved by FDA. Currently on 2nd 28 day cycle of treatment under trial umbrella. Will continue treatment without benefit of trial.
So far, looking good. Major improvements in liver enzymes and tumor shrinkage of several tumors noted after first 28 day cycle. Had no side effects during first cycle. Starting to experience some fatigue during the second cycle, however this fatigue is nothing compared to fatigue from interferon. Also notices variable discomfort in wrists some days.
Next series of scans scheduled after third cycle. Hopeful that scans will show significant improvement through-out.
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- September 12, 2011 at 4:27 pm
I started Zelboraf 8/2/11 as part of clinical trial. 2 weeks into initial month, drug approved by FDA. Currently on 2nd 28 day cycle of treatment under trial umbrella. Will continue treatment without benefit of trial.
So far, looking good. Major improvements in liver enzymes and tumor shrinkage of several tumors noted after first 28 day cycle. Had no side effects during first cycle. Starting to experience some fatigue during the second cycle, however this fatigue is nothing compared to fatigue from interferon. Also notices variable discomfort in wrists some days.
Next series of scans scheduled after third cycle. Hopeful that scans will show significant improvement through-out.
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