Suspicious for Melonma in Situ
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Suspicious for Melonma in Situ

› Forums › Cutaneous Melanoma Community › Suspicious for Melonma in Situ

  • Post
    • July 13, 2018 at 3:10 am
    mbecker
    Participant

    Hi,

    I am new to this. I had a biopsy for a mole on my big toe about a month ago. I have a family history of melonoma and have always been careful to stay out of the sun and use sunscreen.The path report came back 

    FINAL PATHOLOGIC DIAGNOSIS
    SKIN, LEFT FIRST TOE, PUNCH BIOPSY: 
    -ATYPICAL JUNCTIONAL MELANOCYTIC PROLIFERATION, SUSPICIOUS FOR
    MELANOMA IN SITU, FOCALLY
    TRANSECTED LATERALLY (SEE COMMENT) 
    -REEXCISION IS ADVISED

    NUPOOR ANANT GAJJAR M.D.
    ** Report Electronically Signed by NAG **
    Comment
    The clinical images from 7/2017 are reviewed but recent clinical
    images are not available for evaluation. The lesion is atypical
    given the irregular distribution along the junction (despite the
    location being an acral site) and there is suspicion for melanoma
    in situ. Therefore, reexcision (with melanoma in situ-type margins)
    is advised to ensure complete removal of the entire lesion.
    Clinical correlation is advised.

    Consensus diagnosis: Dr. Jessica Chan

    Mic roscopic Description
    Sections demonstrate a thick stratum corneum consistent with acral
    skin overlying a lentiginous junctional proliferation of
    melanocytes. Immunoperoxidase stains Sox-10 and Melan A highlight
    melanocytes and show patchy irregular distribution along the
    junction with melanocytes focally transected at a peripheral edge of the biopsy

    What does focally transected laterally at the peripheral edge mean? was the 

    Does it mean there could be more atypical or melonoma cells past the peripheral edge?

    I am having surgery next week with the 1/2 cm margins.  I am very anxious. I know the success rate is very good if caught early enough.  I appreciate all the knowledge and support this bulletin board offers.

    I wish this had been around when my mom had melanoma.

    Thank you for your support

     

     

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      • July 13, 2018 at 1:30 pm
      Treadlightly
      Participant

      It sounds to me as though the biospy report is saying that the lesion extended beyond the initial biopsy.  It is unusual that there is no mention in the biopsy report of the depth of the invasion of the lesion. However, there is mention of "suspicion of melanoma in situ." It is possible that they need the complete lesion to make the final Breslow's depth determination. 

      Best of luck for a successful treatment!

      Mark 2A

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