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Round 2 ipi – 1st infusion

Forums Cutaneous Melanoma Community Round 2 ipi – 1st infusion

  • Post
    ValinMtl
    Participant

    Well back from Florida after enjoying the good weather, and, of course, where I suffered from scananxiety, nothing is easy.  In November, after completing round 1 with ipi, my CT scan had shown a growth in my left groin…WHATT??   Anyways, doctors believed the beast had metasticized there but thanks to suggestions (thanks fellow ipi warriors) I'm thinking might that lymph node was reacting, I have tried to stay calm.

    Well back from Florida after enjoying the good weather, and, of course, where I suffered from scananxiety, nothing is easy.  In November, after completing round 1 with ipi, my CT scan had shown a growth in my left groin…WHATT??   Anyways, doctors believed the beast had metasticized there but thanks to suggestions (thanks fellow ipi warriors) I'm thinking might that lymph node was reacting, I have tried to stay calm. So after completing the first round of 4 infusions, my cutaneous lesions were drying up and disappearing GREAT since I had over 100 now very few but during the past few months, I saw numerous sub-qs coming up, rather like boils on my right left.  Here's CT scan report and PET concurred.

    The lung bases appear unremarkable.
    The liver, gallbladder, bile ducts, adrenals, kidneys, pancreas, and spleen are unremarkable.
    No abnormality is noted in the bowel. No ascites. Unchanged post-operative scar in the right inguinal region. A right external iliacnode previously measuring 9 mm short axis, today measures 9 mm short axis. There has been interval increase in size of a left inguinal node which previously measured 2.6 x 3.0 cm. Today this measures 4.3 x 6.1 cm. No other enlarged abdominal or pelvic nodes are appreciated.
    No destructive lesion in the bones of the abdomen.
    IMPRESSION:
    Significant interval increase in size of a left inguinal lymph node, as described above. Otherwise no change. 

    So happy no observation in my organs, good reason to celebrate. The Pet scan showed a lot of activity in right leg, they now think it might possibly be good activity (but, of course they are not sure) and perhaps the left groin is reacting as well (but it also might be bad news)…short of a biopsy they can't tell.  They won't remove any lymph nodes in left since my my melanoma is systemic and needs to be solved via drugs rather than surgery so they are leaving it.  Well anyways all this news, enabled me to re-apply for 2nd round.  I am still hoping that left groin problem is a swollen lymph node or, at the very least, the ipi will attack it.

    Thanks to all the support of fellow ipi warriors especially, Jerry, Jim M, Jim B and Jim in Denver, and Donna.  Sharyn, I'm hoping you'll be joining me soon, I gave Michele a big smile for you when I had my first infusion.

    Here's how I feel:

    Round 1 :  Val 1  Mel 0 (down for a few counts)

    AND for Round 2 what I want : Val 2  Mel 0 (down forever)
     

    Val -Stage IV

    off to bed again..rather tired this time around
     

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  • Replies
      ValinMtl
      Participant

      Should mention last CT and PET scan was February after first in November.

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      ValinMtl
      Participant

      Should mention last CT and PET scan was February after first in November.

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      Jim M.
      Participant

      Congratulations Val on the lack of activity in your organs. I'm praying the activity in your leg and groin is due to Ipi working (your immune system working) to rid your body of mel. Thank you for your support as well!! We are in this together.

       God Bless,

       Jim M.

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        Vermont_Donna
        Participant

        Hi Val,

        My last PET/CT scan, two weeks after ipi dose #4 showed inflammatroy response to the Ipi, and also show a new moderately hypermetabolic lymph node or two in the external iliac region…my oncologist said they would read that as response to the Ipi, and I will be rescanned in May and hopefully start round two or Ipi…but now with the FDA approval, not sure there is a round two of Ipi, and I know the clinical trial continues for a minimum of 30 days…I'll still be in my watch and wait. So lots of new questions. I am hoping that your leg is just showing the inflammatory response! You are back to winter here, should have brought some warm sunny weather from Florida!!

        Hugs,

        Vermont_Donna 

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        ValinMtl
        Participant

        Thanks for this information Donna…it puts my overactive mind at rest a little.  Yep, not warm up here..Bill's setting up for his maple syrup run up near Tremblant, I'll join him in a few days.  Val

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        ValinMtl
        Participant

        Thanks for this information Donna…it puts my overactive mind at rest a little.  Yep, not warm up here..Bill's setting up for his maple syrup run up near Tremblant, I'll join him in a few days.  Val

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        Vermont_Donna
        Participant

        Hi Val,

        My last PET/CT scan, two weeks after ipi dose #4 showed inflammatroy response to the Ipi, and also show a new moderately hypermetabolic lymph node or two in the external iliac region…my oncologist said they would read that as response to the Ipi, and I will be rescanned in May and hopefully start round two or Ipi…but now with the FDA approval, not sure there is a round two of Ipi, and I know the clinical trial continues for a minimum of 30 days…I'll still be in my watch and wait. So lots of new questions. I am hoping that your leg is just showing the inflammatory response! You are back to winter here, should have brought some warm sunny weather from Florida!!

        Hugs,

        Vermont_Donna 

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      Jim M.
      Participant

      Congratulations Val on the lack of activity in your organs. I'm praying the activity in your leg and groin is due to Ipi working (your immune system working) to rid your body of mel. Thank you for your support as well!! We are in this together.

       God Bless,

       Jim M.

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      LynnLuc
      Participant

      Very good news and yes the weather is awesome here in Florida…it has been high 80's and sometimes TOO warm for my liking!!

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      LynnLuc
      Participant

      Very good news and yes the weather is awesome here in Florida…it has been high 80's and sometimes TOO warm for my liking!!

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      Sharyn
      Participant

      Hi Val!

      That all sounds great! And I'm delighted you're back in ipi. I had my post-craniotomy SRS on Wed, and I've received the CD of CT scans done in Montreal, and given them to the hospital so the radiologist can do a proper report with comparisons. Once that's done, Dr M will decide if I'm to restart ipi. Is your next infusion on Apr 14? I have a ticket for Mtl on the 13th, so hopefully I can convince them to have me start then, and we'll be infusion buddies. :>) I'll let you know as soon as I hear.

      Hugs

      Sharyn

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        ValinMtl
        Participant

        Yep, April 14th is my next one…Would be great if you can join me, I'm at 11:30 am.  Val

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        ValinMtl
        Participant

        Yep, April 14th is my next one…Would be great if you can join me, I'm at 11:30 am.  Val

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      Sharyn
      Participant

      Hi Val!

      That all sounds great! And I'm delighted you're back in ipi. I had my post-craniotomy SRS on Wed, and I've received the CD of CT scans done in Montreal, and given them to the hospital so the radiologist can do a proper report with comparisons. Once that's done, Dr M will decide if I'm to restart ipi. Is your next infusion on Apr 14? I have a ticket for Mtl on the 13th, so hopefully I can convince them to have me start then, and we'll be infusion buddies. :>) I'll let you know as soon as I hear.

      Hugs

      Sharyn

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