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Next step after biochemo
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Next step after biochemo

› Forums › Mucosal Melanoma Community › Next step after biochemo

  • Post
    • January 26, 2013 at 3:46 pm
    squirrell68
    Participant
      I haven’t posted for a little while but just a quick recap, my brother has received biochemo at the Sheba Centre in Israel for liver and brain mets. His brain mets were treated with SRS in August. He has an unknown primary with suspected mucosal melanoma. He has now completed five cycles and has had a partial response, last MRI was clear and the liver mets reduced by about 80%. He is feeling really well, back at work and exercising. He is BRAF and CKit negative.
      His Oncologist is now recommending ipilimumab as the next step. I would like to hear from any of you who have gone onto ipilimumab after biochemo, I was thinking he would continue on IL2 low dose as maintanance but maybe this is only if you have a CR, we have lots of questions to ask next week but any advice would be great. Tracey
    Viewing 5 reply threads
    • Replies
        • January 28, 2013 at 4:00 am
        jag
        Participant

          Glad to hear that your brother responded to biochemotherapy.  To me it sounds like they are virtually the same.  One study showed that survival increased over time with maintenance biochemotherapy for many patients an average of 1.5 years.  Ipi on the other hand has a better long term remission rate.  I would go the Ipi route if it were me.   

          • January 28, 2013 at 4:00 am
          jag
          Participant

            Glad to hear that your brother responded to biochemotherapy.  To me it sounds like they are virtually the same.  One study showed that survival increased over time with maintenance biochemotherapy for many patients an average of 1.5 years.  Ipi on the other hand has a better long term remission rate.  I would go the Ipi route if it were me.   

            • January 28, 2013 at 4:00 am
            jag
            Participant

              Glad to hear that your brother responded to biochemotherapy.  To me it sounds like they are virtually the same.  One study showed that survival increased over time with maintenance biochemotherapy for many patients an average of 1.5 years.  Ipi on the other hand has a better long term remission rate.  I would go the Ipi route if it were me.   

              • January 28, 2013 at 6:01 am
              Ali
              Participant

                I had a partial response to high dose IL-2 and then we tried IPI (plus Temodar for brain tumors)… My immune system went crazy, tumors started shrinking the first week.  Hope for something similar for you guys. 

                • January 28, 2013 at 6:01 am
                Ali
                Participant

                  I had a partial response to high dose IL-2 and then we tried IPI (plus Temodar for brain tumors)… My immune system went crazy, tumors started shrinking the first week.  Hope for something similar for you guys. 

                  • January 28, 2013 at 6:01 am
                  Ali
                  Participant

                    I had a partial response to high dose IL-2 and then we tried IPI (plus Temodar for brain tumors)… My immune system went crazy, tumors started shrinking the first week.  Hope for something similar for you guys. 

                Viewing 5 reply threads

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