I am a daughter and caregiver from China. My mum(53) was diagnosed with mucosal melanoma last October, she had a surgery with clean margin to remove the tumor but it came back two months ago and we are under immunotherapy ( Nivolumab +Ipilimumab ) now.
Since my mum has low TMB and PD-L1 expression, there are high chances that the immunotherapy would not work for her. In fact, in the first one month treatment the liver mestastisis grew so quickly that we need to have surgery again to remove that. That is why now I want to search for suitable clinical trial for my mum globally.
Researching on clinical trials now, but there seems a lot of trials in process. How is your experience with those trials? Do you have any recommending trials that eligible for someone not respond to immunotherapy combo?