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Are engineered virus’ going to be the next “big thing”?

Forums General Melanoma Community Are engineered virus’ going to be the next “big thing”?

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      SBeattie
      Participant

      As always, thank you Brian!

      SBeattie
      Participant

      As always, thank you Brian!

      SBeattie
      Participant

      As always, thank you Brian!

      ed williams
      Participant

      Thanks Brian, very interesting .I was following the progress of a Cancer Vaccines last year being set up at Harvard University and Dana-Farber. Dr F. Stephen Hodi is running something that seems really interesting where they are Implanting a spoonge like disk made by the Wyss Institute that contained the Patients tumor cells ( dendritic cells scaffolds) was the fancy name. The goverment trial # is NCT01753089 and it started to recruit patients in the fall of 2013. The data in mouse trial was off the charts and I looking into the trial at Bostoon, before being accepted to the BMS trial for Ipi and Nivolumab. You needed to have tumor that was accessable to harvest, which I didn't, so I didn't do anymore follow up at the time. The Wyss Institute has a video on their home page about the science. You need to type in (Implantable Cancer Vaccines Melanoma) to find the video. Hope you find this interesting; Ed.

      ed williams
      Participant

      Thanks Brian, very interesting .I was following the progress of a Cancer Vaccines last year being set up at Harvard University and Dana-Farber. Dr F. Stephen Hodi is running something that seems really interesting where they are Implanting a spoonge like disk made by the Wyss Institute that contained the Patients tumor cells ( dendritic cells scaffolds) was the fancy name. The goverment trial # is NCT01753089 and it started to recruit patients in the fall of 2013. The data in mouse trial was off the charts and I looking into the trial at Bostoon, before being accepted to the BMS trial for Ipi and Nivolumab. You needed to have tumor that was accessable to harvest, which I didn't, so I didn't do anymore follow up at the time. The Wyss Institute has a video on their home page about the science. You need to type in (Implantable Cancer Vaccines Melanoma) to find the video. Hope you find this interesting; Ed.

      ed williams
      Participant

      Thanks Brian, very interesting .I was following the progress of a Cancer Vaccines last year being set up at Harvard University and Dana-Farber. Dr F. Stephen Hodi is running something that seems really interesting where they are Implanting a spoonge like disk made by the Wyss Institute that contained the Patients tumor cells ( dendritic cells scaffolds) was the fancy name. The goverment trial # is NCT01753089 and it started to recruit patients in the fall of 2013. The data in mouse trial was off the charts and I looking into the trial at Bostoon, before being accepted to the BMS trial for Ipi and Nivolumab. You needed to have tumor that was accessable to harvest, which I didn't, so I didn't do anymore follow up at the time. The Wyss Institute has a video on their home page about the science. You need to type in (Implantable Cancer Vaccines Melanoma) to find the video. Hope you find this interesting; Ed.

      Bubbles
      Participant

      Here's a link to an amazing video and article I posted that is working to treat cancer with similar methods.  Pretty impressive –

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2013/12/t-cells-infected-with-genetically.html

      So glad all these smart folks are on our side!  Celeste

      Bubbles
      Participant

      Here's a link to an amazing video and article I posted that is working to treat cancer with similar methods.  Pretty impressive –

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2013/12/t-cells-infected-with-genetically.html

      So glad all these smart folks are on our side!  Celeste

      Bubbles
      Participant

      Here's a link to an amazing video and article I posted that is working to treat cancer with similar methods.  Pretty impressive –

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2013/12/t-cells-infected-with-genetically.html

      So glad all these smart folks are on our side!  Celeste

        RJoeyB
        Participant

        On a related note, Penn and the Wistar Institute here in Philadelphia announced yesterday that they have received a $12 million grant from NCI to fund 4 new melanoma research projects.  The doctor who lead the study highlighted in Celeste's blog entry, Dr. Carl June, is also involved in one of these new projects, which I assume will try to take a similar approach with melanoma.

        http://www.upenn.edu/pennnews/news/penn-medicine-and-wistar-receive-12-million-nci-melanoma-grant-help-fast-track-lab-discoveries-

        When I first heard about the approach for leukemia last year, it reminded me of TIL, except with genetically modified T-cells.  All very neat stuff.  The first patient was a young girl from central Pennsylvania.  Penn is now including it in their local television advertising, highlighting an adult patient who was successfully treated the same way.

        Joe

         

        RJoeyB
        Participant

        On a related note, Penn and the Wistar Institute here in Philadelphia announced yesterday that they have received a $12 million grant from NCI to fund 4 new melanoma research projects.  The doctor who lead the study highlighted in Celeste's blog entry, Dr. Carl June, is also involved in one of these new projects, which I assume will try to take a similar approach with melanoma.

        http://www.upenn.edu/pennnews/news/penn-medicine-and-wistar-receive-12-million-nci-melanoma-grant-help-fast-track-lab-discoveries-

        When I first heard about the approach for leukemia last year, it reminded me of TIL, except with genetically modified T-cells.  All very neat stuff.  The first patient was a young girl from central Pennsylvania.  Penn is now including it in their local television advertising, highlighting an adult patient who was successfully treated the same way.

        Joe

         

        RJoeyB
        Participant

        On a related note, Penn and the Wistar Institute here in Philadelphia announced yesterday that they have received a $12 million grant from NCI to fund 4 new melanoma research projects.  The doctor who lead the study highlighted in Celeste's blog entry, Dr. Carl June, is also involved in one of these new projects, which I assume will try to take a similar approach with melanoma.

        http://www.upenn.edu/pennnews/news/penn-medicine-and-wistar-receive-12-million-nci-melanoma-grant-help-fast-track-lab-discoveries-

        When I first heard about the approach for leukemia last year, it reminded me of TIL, except with genetically modified T-cells.  All very neat stuff.  The first patient was a young girl from central Pennsylvania.  Penn is now including it in their local television advertising, highlighting an adult patient who was successfully treated the same way.

        Joe

         

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