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1 1/2 years NED on Taf/Mek combo, now iritis???
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1 1/2 years NED on Taf/Mek combo, now iritis???

› Forums › General Melanoma Community › 1 1/2 years NED on Taf/Mek combo, now iritis???

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    • July 7, 2017 at 9:17 pm
    mom3girlsFL
    Participant

      Hi everyone! Immediate responder and holding steady since stage 4 in late 2015! Have been on and off a few times but am tolerating very well for the most part.

      Strangely enough my left eye started giving problems a few days ago including pain and bright flashing. I went to the eye doc yesterday who told me my eye was full of "sparkles"… cool, right??!! I've  always gotten compliments on my eyes! Lol…nope! The sparkles were white blood cells and my eye was stage 3 iritis and she wondered why i wasnt in immense pain! Well of course it started hurting after that comment!

      Anyway, i immediately assumed the inflammation was from my auto immune sjogrens but tried to search a little about the taf mek combo and found some scarce info.  Anyone have further info on this?

       

      I was going to tell my rheumy about it but i think i may be making a phone call to onc on monday as well?

      As always you are all in my thoughts and prayers,

      Laurie

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    • Replies
        • July 9, 2017 at 11:17 pm
        Dhva
        Participant

          My son has had uveitis twice while being treated with ipi. I think ocular involvement is also warned about with the Taf/Mek treatments. Definitely worth mentioning to your oncologist. Good luck!

          • July 10, 2017 at 1:06 am
          sister of patient
          Participant

            Hi Laurie,

            It's so cool that you've been NED for 1 1/2 years and able to tolerate the drug combo. I've often thought of Taf/Mek as a "miracle" once I saw the pair in action – I really hope you can continue on it! 

            I had a Novartis site (with side effects listing) bookmarked last year when my sister was on it – https://www.hcp.novartis.com/products/tafinlar-mekinist/  – you may want to check it out – iritis is listed so contactng your onc is best! 

            In other info, it does seem there's more association for it with Taf, so maybe that's the culprit.

            Best wishes on that and may your NED carry on regardless!!

            Barb 

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