The PD-L1 conundrum!!

Thanks for this – really interesting
As someone who finds it best not to know too much about my own position for my sanity I don’t know my expression level. During a moment of stress at my last appointment I asked the question only to be told ‘we don’t test for it in the UK for melanoma’. The view is that the research can’t prove either way so why bother – it’s first line immunotherapy for most so they give it and monitor for results. Apparently there is evidence to support it in some lung cancers and in the UK they test for PD-L1 before determining a treatment plan
Regards
Mark

Thank you Celeste! Your information is invaluable and thank you as always for keeping your finger on the pulse of research. As someone that understands that everyone has their own preference for amount of medical information they can handle, I really think it doesn’t hurt to have ALL this information in the arsenal whether or not they understand exact causation and outcomes yet. The head of Baylor recently told me, why would I bother getting getting genetic testing based on the cyst in my brain (testing for MAPT gene, since it is related to what my father died of and he had similar cyst, PSP). since they don’t have treatment yet. Well that doesn’t mean they won’t have treatment in 10 years and it sure would be helpful information! He didn’t think I could “handle” the information. Well, I’ll be the judge of that, thank you very mich! I thought it was very short-sighted on his part. The current PD-1 knowledge may not contain ALL the answers now, but the research is developing rapidly, it certainly can’t hurt!