Is new pain ever good sign on ipi/nivo combo?
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Is new pain ever good sign on ipi/nivo combo?

› Forums › General Melanoma Community › Is new pain ever good sign on ipi/nivo combo?

  • Post
    • June 17, 2017 at 10:19 pm
    baesill
    Participant

    Hey everyone,

    i just had my fourth round of ipi/nivo just under a week ago and now experiencing pain in the area of my lung that has tumors. My onc is informed and monitoring me.   Just curious if this ever means something good is happening from the ipi/nivo. For those of you that responded, what did it feel like to have your tumors attacked by your immune system? 

    Thanks,

    Monica  

Viewing 1 reply thread
  • Replies
      • June 17, 2017 at 10:54 pm
      jennunicorn
      Participant

      It is common for tumors to enlarge a bit in the beginning, it's like an inflammatory response to the drugs working in them, so it's possible to feel some discomfort if that is happening. 

      • June 17, 2017 at 11:04 pm
      Ridingaroundwith27Jennifers
      Participant

      Hi Monica,

      I had two infusions of the ipi/nivo combo before I had any side effects.  My tumors started shrinking after the first infusion.  i didn't have any pain.  Everyone's experience is so different.  I know that usually tumors swell before they shrink.  Maybe it's possible you are experiencing some pain due to the swelling?  I had only one met on my lung base.  Maybe some places are more painful?  I had many subcutaneous tumors, kidney, adrenal gland and brain.

      I think it is very good that you were able to tolerate all four infusions.  Best wishes to you.

      Jennifer

Viewing 1 reply thread
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.