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WBR

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  • Post
    • August 6, 2015 at 9:22 pm
    evieg
    Participant

    Hi

    I read in a past post that Melanoma is radioresistant …. So chances are Whole Brain radiation is not very effective…. My husband just was told he has 24 tumors in his brain… Going to start on Monday.

    If you have any thought or input… It would be greatly appreciated.

    God Bless all of you.

    Evie

Viewing 5 reply threads
  • Replies
      • August 6, 2015 at 9:34 pm
      mrsaxde
      Participant

      I'm hoping for the best for your husband. Just curious, though. Why radiation, and not one of the immunotherapy drugs? (Yervoy, Keytruda, Opdivo) Or have they already been tried?

      • August 6, 2015 at 9:34 pm
      mrsaxde
      Participant

      I'm hoping for the best for your husband. Just curious, though. Why radiation, and not one of the immunotherapy drugs? (Yervoy, Keytruda, Opdivo) Or have they already been tried?

        • August 6, 2015 at 9:52 pm
        evieg
        Participant

        He has had 4 doses of Keytruda. He was supposed to have his 5 th dose tomorrow. Has been throwing up for the last month… On and off. Dr sent him for a Brain MRI yesterday.(had a brain MRI in May .. Two tiny nodules were there they said wait and recheck). Dr.said Ketruda not working…. ??? Was on Opdivo had Colitis switched to Keytruda… Cancer did spread to small bowel on Keytruda… (Also spread to spleen and lining of stomach on Opdivo) Now this blow out in the brain… Needless to say we are devastated . Nurse told me no more Keytruda.

        • August 6, 2015 at 9:52 pm
        evieg
        Participant

        He has had 4 doses of Keytruda. He was supposed to have his 5 th dose tomorrow. Has been throwing up for the last month… On and off. Dr sent him for a Brain MRI yesterday.(had a brain MRI in May .. Two tiny nodules were there they said wait and recheck). Dr.said Ketruda not working…. ??? Was on Opdivo had Colitis switched to Keytruda… Cancer did spread to small bowel on Keytruda… (Also spread to spleen and lining of stomach on Opdivo) Now this blow out in the brain… Needless to say we are devastated . Nurse told me no more Keytruda.

        • August 6, 2015 at 9:53 pm
        evieg
        Participant

        Thank you!

         

        • August 6, 2015 at 9:53 pm
        evieg
        Participant

        Thank you!

         

        • August 6, 2015 at 11:17 pm
        jamieth29
        Participant
        Is stereotactic or gamma knife a option? I dont know much about brain mets but there is a person on this site who’s mom had like 17-20 brain mets successfully treated by stereo or gamma knife
        • August 6, 2015 at 11:17 pm
        jamieth29
        Participant
        Is stereotactic or gamma knife a option? I dont know much about brain mets but there is a person on this site who’s mom had like 17-20 brain mets successfully treated by stereo or gamma knife
        • August 7, 2015 at 1:53 am
        evieg
        Participant

        Dr said only option!!

        • August 7, 2015 at 1:53 am
        evieg
        Participant

        Dr said only option!!

        • August 7, 2015 at 1:53 am
        evieg
        Participant

        Dr said only option!!

        • August 6, 2015 at 11:17 pm
        jamieth29
        Participant
        Is stereotactic or gamma knife a option? I dont know much about brain mets but there is a person on this site who’s mom had like 17-20 brain mets successfully treated by stereo or gamma knife
        • August 6, 2015 at 9:53 pm
        evieg
        Participant

        Thank you!

         

        • August 6, 2015 at 9:52 pm
        evieg
        Participant

        He has had 4 doses of Keytruda. He was supposed to have his 5 th dose tomorrow. Has been throwing up for the last month… On and off. Dr sent him for a Brain MRI yesterday.(had a brain MRI in May .. Two tiny nodules were there they said wait and recheck). Dr.said Ketruda not working…. ??? Was on Opdivo had Colitis switched to Keytruda… Cancer did spread to small bowel on Keytruda… (Also spread to spleen and lining of stomach on Opdivo) Now this blow out in the brain… Needless to say we are devastated . Nurse told me no more Keytruda.

      • August 6, 2015 at 9:34 pm
      mrsaxde
      Participant

      I'm hoping for the best for your husband. Just curious, though. Why radiation, and not one of the immunotherapy drugs? (Yervoy, Keytruda, Opdivo) Or have they already been tried?

      • August 7, 2015 at 12:23 pm
      Bubbles
      Participant

      Hi Evie, 

      So sorry for what you and your husband are dealing with. I'm guessing your husband is BRAF negative since you didn't mention his having used BRAF inhibitors. But, that is one thing you might consider if possible. At any rate, here is a post that covers a review of brain met management and links within to other brain met info. I realize your husband has already been through a great deal and this may be of little help to you. 

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/07/a-really-good-review-of-treatment-data.html

      Sorry I don't have more to offer. Mostly just wanted to let you know that I am thinking of you and wishing you well. Celeste

       

        • August 7, 2015 at 11:43 pm
        evieg
        Participant

        Celeste, 

         Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

        Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

        My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

        So not looking too good. He will continue to fight.

        thanks again

        • August 7, 2015 at 11:43 pm
        evieg
        Participant

        Celeste, 

         Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

        Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

        My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

        So not looking too good. He will continue to fight.

        thanks again

        • August 7, 2015 at 11:43 pm
        evieg
        Participant

        Celeste, 

         Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

        Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

        My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

        So not looking too good. He will continue to fight.

        thanks again

        • August 7, 2015 at 11:48 pm
        evieg
        Participant

        Celeste, 

         Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

        Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

        My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

        So not looking too good. He will continue to fight.

        thanks again

        • August 7, 2015 at 11:48 pm
        evieg
        Participant

        Celeste, 

         Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

        Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

        My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

        So not looking too good. He will continue to fight.

        thanks again

        • August 7, 2015 at 11:48 pm
        evieg
        Participant

        Celeste, 

         Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

        Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

        My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

        So not looking too good. He will continue to fight.

        thanks again

      • August 7, 2015 at 12:23 pm
      Bubbles
      Participant

      Hi Evie, 

      So sorry for what you and your husband are dealing with. I'm guessing your husband is BRAF negative since you didn't mention his having used BRAF inhibitors. But, that is one thing you might consider if possible. At any rate, here is a post that covers a review of brain met management and links within to other brain met info. I realize your husband has already been through a great deal and this may be of little help to you. 

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/07/a-really-good-review-of-treatment-data.html

      Sorry I don't have more to offer. Mostly just wanted to let you know that I am thinking of you and wishing you well. Celeste

       

      • August 7, 2015 at 12:23 pm
      Bubbles
      Participant

      Hi Evie, 

      So sorry for what you and your husband are dealing with. I'm guessing your husband is BRAF negative since you didn't mention his having used BRAF inhibitors. But, that is one thing you might consider if possible. At any rate, here is a post that covers a review of brain met management and links within to other brain met info. I realize your husband has already been through a great deal and this may be of little help to you. 

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/07/a-really-good-review-of-treatment-data.html

      Sorry I don't have more to offer. Mostly just wanted to let you know that I am thinking of you and wishing you well. Celeste

       

Viewing 5 reply threads
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