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utee72

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      utee72
      Participant

      First let me say that from what I can determine (it IS confusing) it's probably NOT  melanoma but the biopsy is "unusual" are being super cautious and are trying to check deeper just to be sure.

      FYI the world of skin canser especially melanoma is highly analog with lots of room for interpretation in many cases such as yours.

      I'll give you a rough explanation of the terms. FYI I am a formaer MM patient but NOT a pathologist.but have read many reports over the years so i can usually translate their terms.

       

      My comments in ()

      "atypical (unusual) dermal (in the dermal layer eg not deeper-good) epithelioid cell (a cell typical in the dermis that is hard to determine what it is but it is NOT considered to be a melanocyte good), nodular melanocytic proliferation (more dermal cells which ARE melanocytes but they do not show specific signs of melanoma pathology) with indeterminate biological potential ( pathologist cannot see enough abnormality to diagnose but it is "unusual looking"), associated with dermal nevus remnant (nevus = mole)"

      Again probably NOT a melanoma but they are being super cautious especially with a sentinal lymph node biopsy.

      Now you have to wait for the results.

      Odds are in you favor IMO.

       

      JD

       

       

       

      utee72
      Participant

      First let me say that from what I can determine (it IS confusing) it's probably NOT  melanoma but the biopsy is "unusual" are being super cautious and are trying to check deeper just to be sure.

      FYI the world of skin canser especially melanoma is highly analog with lots of room for interpretation in many cases such as yours.

      I'll give you a rough explanation of the terms. FYI I am a formaer MM patient but NOT a pathologist.but have read many reports over the years so i can usually translate their terms.

       

      My comments in ()

      "atypical (unusual) dermal (in the dermal layer eg not deeper-good) epithelioid cell (a cell typical in the dermis that is hard to determine what it is but it is NOT considered to be a melanocyte good), nodular melanocytic proliferation (more dermal cells which ARE melanocytes but they do not show specific signs of melanoma pathology) with indeterminate biological potential ( pathologist cannot see enough abnormality to diagnose but it is "unusual looking"), associated with dermal nevus remnant (nevus = mole)"

      Again probably NOT a melanoma but they are being super cautious especially with a sentinal lymph node biopsy.

      Now you have to wait for the results.

      Odds are in you favor IMO.

       

      JD

       

       

       

      utee72
      Participant

      First let me say that from what I can determine (it IS confusing) it's probably NOT  melanoma but the biopsy is "unusual" are being super cautious and are trying to check deeper just to be sure.

      FYI the world of skin canser especially melanoma is highly analog with lots of room for interpretation in many cases such as yours.

      I'll give you a rough explanation of the terms. FYI I am a formaer MM patient but NOT a pathologist.but have read many reports over the years so i can usually translate their terms.

       

      My comments in ()

      "atypical (unusual) dermal (in the dermal layer eg not deeper-good) epithelioid cell (a cell typical in the dermis that is hard to determine what it is but it is NOT considered to be a melanocyte good), nodular melanocytic proliferation (more dermal cells which ARE melanocytes but they do not show specific signs of melanoma pathology) with indeterminate biological potential ( pathologist cannot see enough abnormality to diagnose but it is "unusual looking"), associated with dermal nevus remnant (nevus = mole)"

      Again probably NOT a melanoma but they are being super cautious especially with a sentinal lymph node biopsy.

      Now you have to wait for the results.

      Odds are in you favor IMO.

       

      JD

       

       

       

      utee72
      Participant

      Melanoma. like most cancers, mutates and thus can mutate to avoid immune system defenses that may be in place for earlier melanomas. Thus the reason to catch it early and WLE remove ALL the primary lesion cells.

      Another later primary may or may not be detected by the immune system depending upon the mutations in the new primary melanocytes. I suspect that most later new primaries fortunately are detected thus the reason for their rarity.

      utee72
      Participant

      Melanoma. like most cancers, mutates and thus can mutate to avoid immune system defenses that may be in place for earlier melanomas. Thus the reason to catch it early and WLE remove ALL the primary lesion cells.

      Another later primary may or may not be detected by the immune system depending upon the mutations in the new primary melanocytes. I suspect that most later new primaries fortunately are detected thus the reason for their rarity.

      utee72
      Participant

      Melanoma. like most cancers, mutates and thus can mutate to avoid immune system defenses that may be in place for earlier melanomas. Thus the reason to catch it early and WLE remove ALL the primary lesion cells.

      Another later primary may or may not be detected by the immune system depending upon the mutations in the new primary melanocytes. I suspect that most later new primaries fortunately are detected thus the reason for their rarity.

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