ricasmith

I want to thank all of you for responding so fast to my original post "what to ask the dermatologist"? . You have put me on the fast track for my frien and I am on the fast track to getting him an appointment for the surgical oncologist. Several of you suggested for me to post the details of the dermatologist's report and I just got it from the hospital. Can you please help me understand the details please and what it means in regards to the stage the melanoma is in ?

Specimen:
A: 1172535. Right temple
B: 1172536. Left Chin

Relevant Clinical Data:
A: Recurrent Neurofibroma
B: Pigmented nevus

Microscopic Diagnosis:
A: Malignant Melanoma: histologically amelanotic
B: Melanocytic nevus – Intradermal type

Description:

Specimen A is a shave biopsy that in the papillary dermis shows some fine fibrils with small spindled nuclei that have no nuclear atypia. However, in the reticular dermis, there is a well-circumscribed neoplasm consisting of nested atypical cells without melanin pigment. These cells are epithelioid appearing, basically round with round to oval nuclei. The mitotic rate is 0 to 1 mitoses per mm2. There are very few tumor infiltrating lymphocytes. There is no evident intravascular invasion by atypical cells. The overlying epidermis has no evident atypical melanocytes. 

Specimen A demonstrates:

A histologically amelanotic malignant melanoma. The neoplasm extends to the base of these sections and the tumor thickness is at least 3.6 mm confirming immunostains, namely vimentin, MART1 and s100 were positive for these cells.

Specimen B is a shave biopsy of a papule that has a normal epidermis. In the characteristics as they proceed deeper. 

There is no nuclear atypia.

There is no evidence of dysplasia or malignancy in specimen B.

END.

I want to thank all of you for responding so fast to my original post "what to ask the dermatologist"? . You have put me on the fast track for my frien and I am on the fast track to getting him an appointment for the surgical oncologist. Several of you suggested for me to post the details of the dermatologist's report and I just got it from the hospital. Can you please help me understand the details please and what it means in regards to the stage the melanoma is in ?

Specimen:
A: 1172535. Right temple
B: 1172536. Left Chin

Relevant Clinical Data:
A: Recurrent Neurofibroma
B: Pigmented nevus

Microscopic Diagnosis:
A: Malignant Melanoma: histologically amelanotic
B: Melanocytic nevus – Intradermal type

Description:

Specimen A is a shave biopsy that in the papillary dermis shows some fine fibrils with small spindled nuclei that have no nuclear atypia. However, in the reticular dermis, there is a well-circumscribed neoplasm consisting of nested atypical cells without melanin pigment. These cells are epithelioid appearing, basically round with round to oval nuclei. The mitotic rate is 0 to 1 mitoses per mm2. There are very few tumor infiltrating lymphocytes. There is no evident intravascular invasion by atypical cells. The overlying epidermis has no evident atypical melanocytes. 

Specimen A demonstrates:

A histologically amelanotic malignant melanoma. The neoplasm extends to the base of these sections and the tumor thickness is at least 3.6 mm confirming immunostains, namely vimentin, MART1 and s100 were positive for these cells.

Specimen B is a shave biopsy of a papule that has a normal epidermis. In the characteristics as they proceed deeper. 

There is no nuclear atypia.

There is no evidence of dysplasia or malignancy in specimen B.

END.

I want to thank all of you for responding so fast to my original post "what to ask the dermatologist"? . You have put me on the fast track for my frien and I am on the fast track to getting him an appointment for the surgical oncologist. Several of you suggested for me to post the details of the dermatologist's report and I just got it from the hospital. Can you please help me understand the details please and what it means in regards to the stage the melanoma is in ?

Specimen:
A: 1172535. Right temple
B: 1172536. Left Chin

Relevant Clinical Data:
A: Recurrent Neurofibroma
B: Pigmented nevus

Microscopic Diagnosis:
A: Malignant Melanoma: histologically amelanotic
B: Melanocytic nevus – Intradermal type

Description:

Specimen A is a shave biopsy that in the papillary dermis shows some fine fibrils with small spindled nuclei that have no nuclear atypia. However, in the reticular dermis, there is a well-circumscribed neoplasm consisting of nested atypical cells without melanin pigment. These cells are epithelioid appearing, basically round with round to oval nuclei. The mitotic rate is 0 to 1 mitoses per mm2. There are very few tumor infiltrating lymphocytes. There is no evident intravascular invasion by atypical cells. The overlying epidermis has no evident atypical melanocytes. 

Specimen A demonstrates:

A histologically amelanotic malignant melanoma. The neoplasm extends to the base of these sections and the tumor thickness is at least 3.6 mm confirming immunostains, namely vimentin, MART1 and s100 were positive for these cells.

Specimen B is a shave biopsy of a papule that has a normal epidermis. In the characteristics as they proceed deeper. 

There is no nuclear atypia.

There is no evidence of dysplasia or malignancy in specimen B.

END.

Hello. I posted this under my original post "what to ask a dermatologist" but I think I may have done something wrong because I haven't received any comments. I hope it is ok to post to your comment because I really need to know what the pathology report means..

Specimen:
A: 1172535. Right temple
B: 1172536. Left Chin

Relevant Clinical Data:
A: Recurrent Neurofibroma
B: Pigmented nevus

Microscopic Diagnosis:
A: Malignant Melanoma: histologically amelanotic
B: Melanocytic nevus – Intradermal type

Description:

Specimen A is a shave biopsy that in the papillary dermis shows some fine fibrils with small spindled nuclei that have no nuclear atypia. However, in the reticular dermis, there is a well-circumscribed neoplasm consisting of nested atypical cells without melanin pigment. These cells are epithelioid appearing, basically round with round to oval nuclei. The mitotic rate is 0 to 1 mitoses per mm2. There are very few tumor infiltrating lymphocytes. There is no evident intravascular invasion by atypical cells. The overlying epidermis has no evident atypical melanocytes.

Specimen A demonstrates:

A histologically amelanotic malignant melanoma. The neoplasm extends to the base of these sections and the tumor thickness is at least 3.6 mm confirming immunostains, namely vimentin, MART1 and s100 were positive for these cells.

Specimen B is a shave biopsy of a papule that has a normal epidermis. In the characteristics as they proceed deeper.

There is no nuclear atypia.

There is no evidence of dysplasia or malignancy in specimen B.

Hello. I posted this under my original post "what to ask a dermatologist" but I think I may have done something wrong because I haven't received any comments. I hope it is ok to post to your comment because I really need to know what the pathology report means..

Specimen:
A: 1172535. Right temple
B: 1172536. Left Chin

Relevant Clinical Data:
A: Recurrent Neurofibroma
B: Pigmented nevus

Microscopic Diagnosis:
A: Malignant Melanoma: histologically amelanotic
B: Melanocytic nevus – Intradermal type

Description:

Specimen A is a shave biopsy that in the papillary dermis shows some fine fibrils with small spindled nuclei that have no nuclear atypia. However, in the reticular dermis, there is a well-circumscribed neoplasm consisting of nested atypical cells without melanin pigment. These cells are epithelioid appearing, basically round with round to oval nuclei. The mitotic rate is 0 to 1 mitoses per mm2. There are very few tumor infiltrating lymphocytes. There is no evident intravascular invasion by atypical cells. The overlying epidermis has no evident atypical melanocytes.

Specimen A demonstrates:

A histologically amelanotic malignant melanoma. The neoplasm extends to the base of these sections and the tumor thickness is at least 3.6 mm confirming immunostains, namely vimentin, MART1 and s100 were positive for these cells.

Specimen B is a shave biopsy of a papule that has a normal epidermis. In the characteristics as they proceed deeper.

There is no nuclear atypia.

There is no evidence of dysplasia or malignancy in specimen B.

Hello. I posted this under my original post "what to ask a dermatologist" but I think I may have done something wrong because I haven't received any comments. I hope it is ok to post to your comment because I really need to know what the pathology report means..

Specimen:
A: 1172535. Right temple
B: 1172536. Left Chin

Relevant Clinical Data:
A: Recurrent Neurofibroma
B: Pigmented nevus

Microscopic Diagnosis:
A: Malignant Melanoma: histologically amelanotic
B: Melanocytic nevus – Intradermal type

Description:

Specimen A is a shave biopsy that in the papillary dermis shows some fine fibrils with small spindled nuclei that have no nuclear atypia. However, in the reticular dermis, there is a well-circumscribed neoplasm consisting of nested atypical cells without melanin pigment. These cells are epithelioid appearing, basically round with round to oval nuclei. The mitotic rate is 0 to 1 mitoses per mm2. There are very few tumor infiltrating lymphocytes. There is no evident intravascular invasion by atypical cells. The overlying epidermis has no evident atypical melanocytes.

Specimen A demonstrates:

A histologically amelanotic malignant melanoma. The neoplasm extends to the base of these sections and the tumor thickness is at least 3.6 mm confirming immunostains, namely vimentin, MART1 and s100 were positive for these cells.

Specimen B is a shave biopsy of a papule that has a normal epidermis. In the characteristics as they proceed deeper.

There is no nuclear atypia.

There is no evidence of dysplasia or malignancy in specimen B.