Melanoma Research Foundation | Roberto | Activity https://forum.melanoma.org/user/roberto/activity/ Activity feed for Roberto. Tue, 21 Apr 2026 23:43:43 -0400 https://buddypress.org/?v= en-US 30 hourly 2 d73158be37e9176181996c35b457d46c Roberto replied to the topic Leptomeningeal Metastases in Melanoma in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/leptomeningeal-metastases-in-melanoma/#post-280466 Mon, 09 Sep 2024 16:05:58 -0400 Thank you very much for your words. We are doing intrathecal nivolumab (phase 1) with temozolomide.

Before the disease reached the leptomeningeal region, she had a very good response to chemotherapy, with the disease regressing and disappearing in the rest of the body, but it seems that chemotherapy does not act on the leptomeningeal region.

]]> 4927c4e49b733b782ca08b2d41fce6ac Roberto replied to the topic Leptomeningeal Metastases in Melanoma in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/leptomeningeal-metastases-in-melanoma/#post-280450 Sun, 01 Sep 2024 15:12:47 -0400 Thank you very much, Ed Williams
It’s not very encouraging, but unfortunately it’s reality.

]]> 6560da7de66472f20352fe518a3e2e9e Roberto started the topic Leptomeningeal Metastases in Melanoma in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/leptomeningeal-metastases-in-melanoma/ Wed, 28 Aug 2024 22:47:00 -0400 Hello friends,
It’s been a while since I’ve participated in the discussions here. The forum has changed so much in that time.
I wanted to know if anyone could give me some light on Leptomeningeal Metastases in Melanoma. After dozens of treatments against the “beast”, my wife was diagnosed with Leptomeningeal Metastases. Everything I’ve read is…Read more

]]> 3f0b42cafc5afbefdc2f20f9c6fdd5c0 Roberto replied to the topic Lenvatinib in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/lenvatinib/#post-280256 Tue, 21 May 2024 02:21:13 -0400 Hélio,
My wife used levantinib for about 2 years with Pembro. The combination of these two drugs helped a lot in stopping the progression of the disease. Let’s say: if the disease comes at a speed of 100km/h, the treatment reduces it to 5 or 10km/h. The problem is that after a while the side effects increase a lot, it seems that the body…Read more

]]> 6ef4a7c9bf40338799b126807e1adda6 Roberto replied to the topic For Roberto in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/for-roberto/#post-279304 Wed, 04 Oct 2023 06:49:53 -0400 Thank you Celeste for your advice.
Unfortunately, we do not have any intralesional medication approved in Brazil for melanoma. There was a clinical trial with T-Vec, but Mariana did not qualify. We are out of options. Our goal now is to control the pain and treat the colitis. 30mg of morphine every 4 hours is not working.

]]> fda41ab484c77f0a8a38f0e99cbe4eb8 Roberto replied to the topic For Roberto in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/for-roberto/#post-279271 Wed, 27 Sep 2023 04:47:52 -0400 Dear Celeste,how good it is to talk and learn from you

it took me a while to respond because Mariana, my wife, was hospitalized after my message. She had a series of 4 seizures, within a 40-minute interval, which according to doctors, was probably due to immunotherapy with opdualag and Lenvatinib, since the MRI scans did not detect any brain…Read more

]]> 866b270ce616c238019d9234398565e1 Roberto replied to the topic New.. Trying to understand in the forum General Melanoma Community https://forum.melanoma.org/forums/topic/new-trying-to-understand/#post-279210 Sat, 16 Sep 2023 05:47:48 -0400 Dear Bubbles,

My wife is one of those who went through all these treatments that you discussed on your blog. In fact, she went through some that are not there, such as isolated limb perfusion (this one 3 times) and TIL. let’s go, in order:
1- Surgery,
2- ipilimumab,
3- nivolumab,
4- ipilimumab + nivolumab,
5- isolated limb perfusion…Read more

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