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Re: Looking for MEK responders

Forums General Melanoma Community Looking for MEK responders Re: Looking for MEK responders


      Hi Lori, 

      It is wonderful to hear from you and others on the MEK trial.   Brents rash is NASTY and painful.  We saw a Derm last week and he is using cremes and antiboticis.  He gets Scans at Md Anderson on the the 16th of this month.  My research shows me that it is pretty clear that the combination trials are the way to go.  The mutations seem to be able to change right in the middle of treatment.  Braf one month ….not braf the later.   Brent was tested and was Braf negative as well as C-Kit negative .  He got on the Mek trial anyway.  It was not a requirement to be positive for Braf.  We want to know that if he progresses he can swith to a combo trial but I am finding out that it is almost impossible at this time.   I am trying not to worry about down the road and just get through to next set of scans.

      Sharon (Brents Wife)


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