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Re: Hoffman-La Roche BRAF inhibitor trial Participants

Forums Cutaneous Melanoma Community Hoffman-La Roche BRAF inhibitor trial Participants Re: Hoffman-La Roche BRAF inhibitor trial Participants

    Hi Molly,

    I started the same trial on June 14 and was randomized to the RO5185426.  My first 5 days were a piece of cake and then I too broke out in a rash ALL over my body.  I was extremely sensitive to the hot weather and to the sun.  I could almost feel myslef blister from direct sunlight.  By the end of the first week I had arthritis so bad in my hands, arms, feet and legs that my husband had to undress me.   Walking was painful.   During the first three weeks I also had fevers at the end of the day.   Eventually it all subsided and now I deal with arthritic pain that changes locations in my body weekly.  One day it might be in my hand that I can't even open due to pain or the next week my shins, crazy movement…  

    The good news is that after 6 weeks my tumors in the pluera were shrinking.  I have stuck it out and I feel I can live with the aches and pains.  (By the way, the rash went away completely after 2.5 weeks.)

    I hope you can try it again.   

    Take care,

    Shelly in SW

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